Diseases associated with tobacco use constitute a major health problem worldwide. Upon
cessation of tobacco use, an unpleasant withdrawal syndrome occurs in dependent …

Much evidence indicates that individuals use tobacco primarily to experience the
psychopharmacological properties of nicotine and that a large proportion of smokers …

E‐cigarettes, which deliver vaporized nicotine, have dramatically risen in popularity in recent
years, despite many unanswered questions about safety, efficacy in reducing dependence …

Introduction Nicotine and tobacco use remain high both globally and in the United States,
contributing to large health care expenditures. With a rise in e-cigarette use, it is important to …

Rationale Non-contingent chronic nicotine exposure procedures have evolved rapidly in
recent years, culminating in electronic nicotine delivery systems (ENDS or e-cigarettes) to …

The debate about electronic cigarettes is dividing healthcare professionals, policymakers,
manufacturers, and communities. A key limitation in our understanding of the cause and …

Although inhaled exposure to drugs is a prevalent route of administration for human
substance abusers, preclinical models that incorporate inhaled exposure to psychomotor …

Nicotine is the primary addictive substance in tobacco smoke and electronic cigarette (e-cig)
vapour. Methodological limitations have made it difficult to compare the role of the nicotine …

Nicotine use is a leading cause of preventable deaths worldwide, and most of those who
attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery …

Electronic cigarettes (E-cig) use is increasing rapidly, particularly among youths. Animal
models for E-cig exposure with pharmacokinetics resembling human E-cig users are …