[HTML][HTML] Sperm ion transporters and channels in human asthenozoospermia: genetic etiology, lessons from animal models, and clinical perspectives

E Cavarocchi, M Whitfield, F Saez, A Touré - International journal of …, 2022 - mdpi.com
In mammals, sperm fertilization potential relies on efficient progression within the female
genital tract to reach and fertilize the oocyte. This fundamental property is supported by the …

Microfluidics facilitating the use of small extracellular vesicles in innovative approaches to male infertility

DM Goss, SA Vasilescu, G Sacks, DK Gardner… - Nature Reviews …, 2023 - nature.com
Sperm are transcriptionally and translationally quiescent and, therefore, rely on the seminal
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …

HBFP: a new repository for human body fluid proteome

D Shao, L Huang, Y Wang, X Cui, Y Li, Y Wang… - Database, 2021 - academic.oup.com
Body fluid proteome has been intensively studied as a primary source for disease biomarker
discovery. Using advanced proteomics technologies, early research success has resulted in …

Tumour‐derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8‐mediated creatine import in NPM1‐mutated acute myeloid …

M Peng, J Ren, Y Jing, X Jiang, Q Xiao… - Journal of …, 2021 - Wiley Online Library
Acute myeloid leukaemia (AML) carrying nucleophosmin (NPM1) mutations has been
defined as a distinct entity of acute leukaemia. Despite remarkable improvements in …

[HTML][HTML] Seminal extracellular vesicles subsets modulate gene expression in cumulus cells of porcine in vitro matured oocytes

Y Mateo-Otero, M Yeste, J Roca, M Llavanera… - Scientific Reports, 2022 - nature.com
Seminal plasma (SP), a fluid composed mainly by secretions from accessory sex glands,
contains a heterogenous population of extracellular vesicles (EVs), involved in several …

[HTML][HTML] Immunophenotype profile by flow cytometry reveals different subtypes of extracellular vesicles in porcine seminal plasma

I Barranco, A Alvarez-Barrientos, A Parra… - Cell Communication and …, 2024 - Springer
Background Porcine seminal plasma (SP) is endowed with a heterogeneous population of
extracellular vesicles (sEVs). This study evaluated the immunophenotypic profile by high …

Reassessment of the proteomic composition and function of extracellular vesicles in the seminal plasma

H Wang, Y Zhu, C Tang, Z Zhou, Z Wang, Z Li… - …, 2022 - academic.oup.com
Seminal plasma contains a high concentration of extracellular vesicles (EVs). The
heterogeneity of small EVs or the presence of nonvesicular extracellular matter (NV) pose …

[HTML][HTML] Altered ureido protein modification profiles in seminal plasma extracellular vesicles of non-normozoospermic men

R Roy, C Lorca, M Mulet, JA Sánchez Milán… - Frontiers in …, 2023 - frontiersin.org
Introduction Extracellular vesicles (EVs) have been recognized as key players in numerous
physiological functions. These vesicles alter their compositions attuned to the health and …

Proteomic analysis of koala (phascolarctos cinereus) spermatozoa and prostatic bodies

DA Skerrett‐Byrne, AL Anderson, L Hulse, C Wass… - …, 2021 - Wiley Online Library
The aims of this study were to investigate the proteome of koala spermatozoa and that of the
prostatic bodies with which they interact during ejaculation. For this purpose, spermatozoa …

Extracellular vesicles from seminal plasma interact with T cells in vitro and drive their differentiation into regulatory T‐cells

X Zhang, PF Greve, TTN Minh… - Journal of …, 2024 - Wiley Online Library
Seminal plasma induces immune tolerance towards paternal allogenic antigens within the
female reproductive tract and during foetal development. Recent evidence suggests a role …