Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Schizophrenia is a complex neuropsychiatric syndrome with a heterogeneous genetic,
neurobiological, and phenotypic profile. Currently, no objective biological measures—that is …

Purpose Evolving treatments, disease phenotypes, and biology, together with a changing
drug development environment, have created the need to revise castration-resistant prostate …

With the emergence of genomic profiling technologies and selective molecular targeted
therapies, biomarkers play an increasingly important role in the clinical management of …

Emerging smartphone-based point-of-care tests (POCTs) are cost-effective, precise, and
easy to implement in resource-limited areas. Thus, they are considered a potential …

Liquid biopsy has been established as a powerful, minimally invasive, tool to detect clinically
actionable aberrations across numerous cancer types in real-time. With the development of …

Importance A blood test to determine whether to treat patients with metastatic castration-
resistant prostate cancer (mCRPC) with an androgen receptor signaling (ARS) inhibitor or …

Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and
express genetic information, which play central roles in diverse cellular events and diseases …

Understanding the molecular landscape of cancer has facilitated the development of
diagnostic, prognostic, and predictive biomarkers for clinical oncology. Developments in …

BACKGROUND Biomarkers are playing increasingly important roles in the detection and
management of patients with cancer. Despite an enormous number of publications on …