Neutrophils act as the first line of defense during infection and inflammation. Once activated,
they are able to fulfil numerous tasks to fight inflammatory insults while keeping a balanced …

Bacterial biofilms efficiently evade immune defenses, greatly complicating the prognosis of
chronic infections. How methicillin-resistant Staphylococcus aureus (MRSA) biofilms evade …

Staphylococcus aureus is an opportunistic pathogen and chief among bloodstream-infecting
bacteria. S. aureus produces an array of human-specific virulence factors that may …

Staphylococcus aureus bi-component pore-forming leukocidins are secreted toxins that
directly target and lyse immune cells. Intriguingly, one of the leukocidins, Leukocidin AB …

Staphylococcus aureus is a versatile bacterial pathogen that can cause significant disease
burden and mortality. Like other pathogens, S. aureus must adapt to its environment to …

Therapy for bacteremia caused by Staphylococcus aureus is often ineffective, even when
treatment conditions are optimal according to experimental protocols. Adapted subclones …

The pathogen Staphylococcus aureus colonizes and infects a variety of different sites within
the human body. To adapt to these different environments, S. aureus relies on a complex …

Bacterial biofilms are linked with chronic infections and have properties distinct from those of
planktonic, single-celled bacteria. The virulence mechanisms associated with …

Pathogenesis of Staphylococcus aureus is increasingly recognized to be driven by powerful
toxins. Staphylococcus aureus employs up to six pore-forming toxins to subvert the human …

Infections caused by the Gram-positive bacterium Staphylococcus aureus remain a
significant health threat globally. The production of bicomponent pore-forming leukocidins …