With almost 20 million new cases per year, cancer constitutes one of the most important
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …

The rat has been extensively used as a small animal model. Many genetically engineered
rat models have emerged in the last two decades, and the advent of gene-specific …

Biosensors based on endonuclease Cas12 provide high specificity in pathogen detection.
Sensitive detection using Cas12-based assays can be achieved using trans-cleaved DNA …

Protein amyloid nanofibers provide a biocompatible platform for the development of
functional nanomaterials. However, the functionalities generated up to date are still limited …

Since its discovery in 2012, the clustered regularly interspaced short palindromic repeats
(CRISPR) and CRISPR-associated protein 9 (Cas9) system has supposed a promising …

Proteinaceous nanovaccine delivery systems have significantly promoted the development
of various high-efficiency vaccines. However, the widely used method of coupling the …

Recently, there have been enormous advances in nano-delivery materials, especially safer
and more biocompatible protein-based nanoparticles. Generally, proteinaceous …

Antibody–drug conjugates (ADCs) are biologically targeted drugs composed of antibodies
and cytotoxic drugs connected by linkers. These innovative compounds enable precise drug …

Strategies that mimic the spatial complexity of natural tissues can provide cellular scaffolds
to probe fundamental questions in cell biology and offer new materials for regenerative …

Secondary amines, due to their reactivity, can transform protein templates into catalytically
active entities, accelerating the development of artificial enzymes. However, existing …