While extracellular somatic action potentials from freely moving rats have been well
characterized, axonal activity has not. We have recently reported extracellular tetrode …

Photoactivated genetically encoded voltage indicators (GEVIs) have the potential to enable
optically sectioned voltage imaging at the intersection of a photoactivation beam and an …

Genetically encoded voltage sensors expand the optogenetics toolkit into the important
realm of electrical recording, enabling researchers to study the dynamic activity of complex …

In cortical pyramidal neurons, backpropagating action potentials (bAPs) supply Ca2+ to
synaptic contacts on dendrites. To determine whether the efficacy of AP backpropagation …

Voltage-sensitive fluorescence indicators enable tracking neuronal electrical signals
simultaneously in multiple neurons or neuronal subcompartments difficult to access with …

Background Recent progress in electrophysiological and optical methods for neuronal
recordings provides vast amounts of high-resolution data. In parallel, the development of …

For many years, synaptic transmission was considered as information transfer between
presynaptic neuron and postsynaptic cell. At the synaptic level, it was thought that dendritic …

Prefrontal layer 6 (L6) pyramidal neurons play an important role in the adult control of
attention, facilitated by their strong activation by nicotinic acetylcholine receptors. These …

Wide-field single photon voltage-sensitive dye (VSD) imaging of brain slice preparations is a
useful tool to assess the functional connectivity in neural circuits. Due to the fractional …

Robust voltage imaging in tissue remains a technical challenge. Existing combinations of
genetically encoded voltage indicators (GEVIs) and microscopy techniques cannot …