Mycoplasmas as host pantropic and specific pathogens: clinical implications, gene transfer, virulence factors, and future perspectives

A Dawood, SA Algharib, G Zhao, T Zhu, M Qi… - Frontiers in cellular …, 2022 - frontiersin.org
Mycoplasmas as economically important and pantropic pathogens can cause similar clinical
diseases in different hosts by eluding host defense and establishing their niches despite …

Recent Developments in Vaccines for Bovine Mycoplasmoses Caused by Mycoplasma bovis and Mycoplasma mycoides subsp. mycoides

K Dudek, E Szacawa, RAJ Nicholas - Vaccines, 2021 - mdpi.com
Two of the most important diseases of cattle are caused by mycoplasmas. Mycoplasma
bovis is a world-wide bovine pathogen that can cause pneumonia, mastitis and arthritis. It …

Proteomics approaches: A review regarding an importance of proteome analyses in understanding the pathogens and diseases

M Zubair, J Wang, Y Yu, M Faisal, M Qi… - Frontiers in Veterinary …, 2022 - frontiersin.org
Proteomics is playing an increasingly important role in identifying pathogens, emerging and
re-emerging infectious agents, understanding pathogenesis, and diagnosis of diseases …

Novel mycoplasma nucleomodulin MbovP475 decreased cell viability by regulating expression of CRYAB and MCF2L2

G Zhao, D Lu, S Wang, H Zhang, X Zhu, Z Hao… - Virulence, 2022 - Taylor & Francis
Nucleomodulins are secreted bacterial proteins whose molecular targets are located in host
cell nuclei. They are gaining attention as critical virulence factors that either modify the …

The Mycoplasma spp. 'Releasome': A New Concept for a Long-Known Phenomenon

P Gaurivaud, F Tardy - Frontiers in Microbiology, 2022 - frontiersin.org
The bacterial secretome comprises polypeptides expressed at the cell surface or released
into the extracellular environment as well as the corresponding secretion machineries …

Comparative Proteomic Analysis of Secretory Proteins of Mycoplasma bovis and Mycoplasma mycoides subsp. mycoides Investigates Virulence and Discovers …

AS Dawood, G Zhao, Y He, D Lu, S Wang, H Zhang… - Veterinary …, 2023 - mdpi.com
Simple Summary Mycoplasma bovis (M. bovis) and Mycoplasma mycoides subsp. mycoides
(Mmm) are the most important pathogenic mycoplasma species. But, the limited knowledge …

Identification of potential nucleomodulins of Mycoplasma bovis by direct biotinylation and proximity-based biotinylation approaches

D Lu, J Chen, M Zhang, Y Fu, A Raheem… - Frontiers in …, 2024 - frontiersin.org
Mycoplasma bovis (M. bovis) is a significant bovine pathogen associated with various
diseases, including bovine bronchopneumonia and mastitis resulting in substantial …

PncsHub: a platform for annotating and analyzing non-classically secreted proteins in Gram-positive bacteria

W Dai, J Li, Q Li, J Cai, J Su… - Nucleic Acids …, 2022 - academic.oup.com
From industry to food to health, bacteria play an important role in all facets of life. Some of
the most important bacteria have been purposely engineered to produce commercial …

Comparative Secretome Analyses of Mycoplasma bovis Virulent and Attenuated Strains Revealed MbovP0145 as a Promising Diagnostic Biomarker

H Zhang, G Hu, D Lu, G Zhao, Y Zhang… - Frontiers in Veterinary …, 2021 - frontiersin.org
Mycoplasmas are successful pathogens both in humans as well as in animals. In cattle,
Mycoplasma bovis (M. bovis) is known to be responsible for serious health complications …

MbovP0725, a secreted serine/threonine phosphatase, inhibits the host inflammatory response and affects metabolism in Mycoplasma bovis

H Zhang, Y Zhang, D Lu, X Chen, Y Chen, C Hu… - Msystems, 2024 - Am Soc Microbiol
Mycoplasma species are able to produce and release secreted proteins, such as toxins,
adhesins, and virulence-related enzymes, involved in bacteria adhesion, invasion, and …