[HTML][HTML] Links between testosterone, oestrogen, and the growth hormone/insulin-like growth factor axis and resistance exercise muscle adaptations

N Gharahdaghi, BE Phillips, NJ Szewczyk… - Frontiers in …, 2021 - frontiersin.org
Maintenance of skeletal muscle mass throughout the life course is key for the regulation of
health, with physical activity a critical component of this, in part, due to its influence upon key …

Skeletal muscle regeneration in cardiotoxin-induced muscle injury models

Y Wang, J Lu, Y Liu - International journal of molecular sciences, 2022 - mdpi.com
Skeletal muscle injuries occur frequently in daily life and exercise. Understanding the
mechanisms of regeneration is critical for accelerating the repair and regeneration of …

DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

M Abayev-Avraham, Y Salzberg, D Gliksberg… - Nature …, 2023 - nature.com
Molecular chaperones are essential cellular components that aid in protein folding and
preventing the abnormal aggregation of disease-associated proteins. Mutations in one such …

Time course of immune response and immunomodulation during normal and delayed healing of musculoskeletal wounds

PJ Muire, LH Mangum, JC Wenke - Frontiers in immunology, 2020 - frontiersin.org
Single trauma injuries or isolated fractures are often manageable and generally heal without
complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns …

The interaction of force and repetition on musculoskeletal and neural tissue responses and sensorimotor behavior in a rat model of work-related musculoskeletal …

MF Barbe, S Gallagher, VS Massicotte, M Tytell… - BMC musculoskeletal …, 2013 - Springer
Background We examined the relationship of musculoskeletal risk factors underlying force
and repetition on tissue responses in an operant rat model of repetitive reaching and pulling …

lncRNA RMRP Prevents Mitochondrial Dysfunction and Cardiomyocyte Apoptosis via the miR-1-5p/hsp70 Axis in LPS-Induced Sepsis Mice

Y Han, Y Cai, X Lai, Z Wang, S Wei, K Tan, M Xu, H Xie - Inflammation, 2020 - Springer
Both long non-coding RNA (lncRNA) RMRP and heat shock protein (HSP) 70 have been
known to play crucial roles in inflammation. The present study investigated the roles of …

Role of macrophages during skeletal muscle regeneration and hypertrophy—Implications for immunomodulatory strategies

C Bernard, A Zavoriti, Q Pucelle… - Physiological …, 2022 - Wiley Online Library
Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to
raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a …

Role of heat shock proteins 70/90 in exercise physiology and exercise immunology and their diagnostic potential in sports

K Krüger, T Reichel, C Zeilinger - Journal of Applied …, 2019 - journals.physiology.org
Heat shock proteins (HSPs) are molecular chaperones facilitating the unfolding or folding of
secondary structures of proteins, their client proteins, in cellular stress situations. Various …

Modulating exercise-induced hormesis: does less equal more?

JM Peake, JF Markworth, K Nosaka… - Journal of Applied …, 2015 - journals.physiology.org
Hormesis encompasses the notion that low levels of stress stimulate or upregulate existing
cellular and molecular pathways that improve the capacity of cells and organisms to …

Transcriptome response of human skeletal muscle to divergent exercise stimuli

JM Dickinson, AC D'Lugos… - Journal of Applied …, 2018 - journals.physiology.org
Aerobic (AE) and resistance exercise (RE) elicit unique adaptations in skeletal muscle that
have distinct implications for health and performance. The purpose of this study was to …