The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin)
and myelin phenotypes, which are specialized to meet the needs of small and large …

The Transforming Growth Factor-beta (TGF-β) family plays relevant roles in the regulation of
different cellular processes that are essential for tissue and organ homeostasis. In the case …

Cancer progression involves the gradual loss of a differentiated phenotype and acquisition
of progenitor and stem-cell-like features. Here, we provide novel stemness indices for …

Schwann cells respond to nerve injury by cellular reprogramming that generates cells
specialized for promoting regeneration and repair. These repair cells clear redundant …

Chemoresistance remains a major complication of cancer treatments. Recent data provide
strong evidence that chemoresistance is linked to epithelial–mesenchymal transition (EMT) …

Transforming growth factor-β (TGF-β) promotes tumor invasion and metastasis by inducing
epithelial-mesenchymal transition (EMT). EMT is often related with acquisition of stemness …

ENCODE comprises thousands of functional genomics datasets, and the encyclopedia
covers hundreds of cell types, providing a universal annotation for genome interpretation …

The prominent role of CD44 in tumor cell signaling together with its establishment as a
cancer stem cell (CSC) marker for various tumor entities imply a key role for CD44 in CSC …

Abstract m6A RNA methylation is an emerging epigenetic modification, and its potential role
in immunity and stemness remains unknown. Based on 17 widely recognized m6A …

Background Lung cancer is the leading cause of cancer related deaths and its incidence is
highly correlated with cigarette smoking. Nicotine, the addictive component of tobacco …