siRNA-based strategies to combat drug resistance in gastric cancer
AQ Khaleel, MY Alshahrani, JA Rizaev, H Malathi… - Medical Oncology, 2024 - Springer
Chemotherapy is a key treatment option for gastric cancer, but over 50% of patients develop
either inherent or acquired resistance to these drugs, resulting in a 5-year survival rate of …
either inherent or acquired resistance to these drugs, resulting in a 5-year survival rate of …
[HTML][HTML] Deciphering drug resistance in gastric cancer: Potential mechanisms and future perspectives
J Liu, Q Yuan, H Guo, H Guan, Z Hong… - Biomedicine & …, 2024 - Elsevier
Gastric cancer (GC) is a malignant tumor that originates from the epithelium of the gastric
mucosa. The latest global cancer statistics show that GC ranks fifth in incidence and fourth in …
mucosa. The latest global cancer statistics show that GC ranks fifth in incidence and fourth in …
Plasma cell-free tumor methylome as a biomarker in solid tumors: biology and applications
DNA methylation is a fundamental mechanism of epigenetic control in cells and its
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …
[HTML][HTML] lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma
Z Ting, Z Wu, C Yang, Z Li, H Huang, J Gan, N Li… - Non-coding RNA …, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) play a crucial role in tumor generation and progression.
However, the exact functional significance and underlying molecular mechanism by which …
However, the exact functional significance and underlying molecular mechanism by which …
Roles of post-translational modifications of UHRF1 in cancer
L Gu, Y Fu, X Li - Epigenetics & Chromatin, 2024 - Springer
UHRF1 as a member of RING-finger type E3 ubiquitin ligases family, is an epigenetic
regulator with five structural domains. It has been involved in the regulation of a series of …
regulator with five structural domains. It has been involved in the regulation of a series of …
[HTML][HTML] A review on the role of KCNQ1OT1 lncRNA in human disorders
KCNQ1OT1 is an lncRNA located within KCNQ1 gene on chromosome 11p15. 5. This
lncRNAs participates in the pathogenesis of a diversity of cancers as well as non-cancerous …
lncRNAs participates in the pathogenesis of a diversity of cancers as well as non-cancerous …
[HTML][HTML] Role of the NLRP3 inflammasome in gynecological disease
X Zheng, D Zhao, Y Jin, Y Liu, D Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The NLR family pyrin domain containing 3 (NLRP3) inflammasome is involved in the innate
immune system and is a three-part macromolecular complex comprising the NLRP3 protein …
immune system and is a three-part macromolecular complex comprising the NLRP3 protein …
Endocrine toxicity of atrazine and its underlying mechanisms
H Zhao, H Qian, J Cui, Z Ge, J Shi, Y Huo, Y Zhang… - Toxicology, 2024 - Elsevier
Atrazine (ATR) is one of the most widely utilized herbicides globally and is prevalent in the
environment due to its extensive use and long half-life. It can infiltrate the human body …
environment due to its extensive use and long half-life. It can infiltrate the human body …
Prognostic significance of MALAT1 in clear cell renal cell carcinoma based on TCGA and GEO
K Liu, Y Gao, Q Zhang - Medicine, 2023 - journals.lww.com
Long noncoding RNAs metastasis-associated lung adenocarcinoma transcript 1 (MALAT1)
can regulate tumorigenesis and progression of various cancers. However, there is little …
can regulate tumorigenesis and progression of various cancers. However, there is little …
LncRNA-Mediated Regulation of Cisplatin Response in Breast Cancer
S Azizidoost, M Sheykhi-Sabzehpoush… - … -Research and Practice, 2024 - Elsevier
Breast cancer is a prevalent and aggressive disease characterized by high metastasis,
recurrence, and mortality rates. While cisplatin is an effective chemotherapy drug, its use is …
recurrence, and mortality rates. While cisplatin is an effective chemotherapy drug, its use is …