Advances in oral drug delivery for regional targeting in the gastrointestinal tract-influence of physiological, pathophysiological and pharmaceutical factors

S Hua - Frontiers in pharmacology, 2020 - frontiersin.org
The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …

Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

Expandable drug delivery system for gastric retention based on shape memory polymers: Development via 4D printing and extrusion

A Melocchi, M Uboldi, N Inverardi… - International journal of …, 2019 - Elsevier
Several diseases would benefit from prolonged drug release provided by systems retained
in the stomach for extended time periods. Expandable gastroretentive devices are …

Utilizing 4D printing to design smart gastroretentive, esophageal, and intravesical drug delivery systems

DB Mahmoud… - Advanced Healthcare …, 2023 - Wiley Online Library
The breakthrough of 3D printing in biomedical research has paved the way for the next
evolutionary step referred to as four dimensional (4D) printing. This new concept utilizes the …

Enhancing Oral Absorption of Orlistat through Gastroretentive Mucoadhesive Pellets: Formulation and Evaluation

UK Thummala, PS Vallabhareddy, PNK Sarella - Journal of Clinical and …, 2023 - jcpr.in
Aim: The aim of this study was to develop gastroretentive mucoadhesive pellets of Orlistat to
improve its oral bioavailability and enhance its absorption. Methods: Orlistat pellets were …

[HTML][HTML] Features and facts of a gastroretentive drug delivery system-a review

K Vinchurkar, J Sainy, MA Khan, M Sheetal… - Turkish journal of …, 2022 - ncbi.nlm.nih.gov
Abstract English oral delivery of drug was the commonly used modality because of patient
compliance and ease of administration. After oral administration of any drug, its …

A review on curcumin colon-targeted oral drug delivery systems for the treatment of inflammatory bowel disease

HS Sardou, PR Vosough, M Abbaspour, A Akhgari… - …, 2023 - Springer
Synthetic drugs and monoclonal antibodies are the typical treatments to combat
inflammatory bowel disease (IBD). However, side effects are present when these treatments …

Highlighting the impact of chitosan on the development of gastroretentive drug delivery systems

MPC de Souza, RM Sábio, T de Cassia Ribeiro… - International Journal of …, 2020 - Elsevier
The development of gastroretentive systems have been growing lately due to the high
demand for carriers that increase drug bioavailability and therapeutic effectiveness after oral …

Administration strategies and smart devices for drug release in specific sites of the upper GI tract

M Uboldi, A Melocchi, S Moutaharrik, L Palugan… - Journal of Controlled …, 2022 - Elsevier
Targeting the release of drugs in specific sites of the upper GI tract would meet local
therapeutic goals, improve the bioavailability of specific drugs and help overcoming …

Copper (ii)-MOFs for bio-applications

J Aguila-Rosas, D Ramos… - Chemical …, 2023 - pubs.rsc.org
The recent development and implementation of copper-based metal–organic frameworks in
biological applications are reviewed. The advantages of the presence of copper in MOFs for …