This review examined a collection of studies regarding the molecular properties of some
polyene antibiotic molecules as well as their properties in solution and in particular …

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Benznidazole and nifurtimox are the two approved drugs for their treatment, but both …

Amphotericin B, an antifungal drug with a long history of use, forms fungicidal ion-permeable
channels across cell membranes. Using solid-state nuclear magnetic resonance …

Ergosterol-targeting amphotericin B (AmB) is the first line of defense for life-threatening
fungal infections. Two models have been proposed to illustrate AmB assembly in the cell …

Amphotericin-like glycosylated polyene macrolides (GPMs) are a clinically and industrially
important family of natural products, but the mechanisms by which they exert their …

Although lateral and inter-leaflet lipid–lipid interactions in cell membranes play roles in
maintaining asymmetric lipid bilayers, the molecular basis of these interactions is largely …

A novel mucomimetic and biocompatible nanocarrier, carboxymethyl tamarind seed
polysaccharide (CMTSP) nanoparticles, were synthesized using ionic gelation. The …

The higher molecular weight and low solubility of amphotericin B (AmB) hinders its topical
administration. The aim of this study was to incorporate Bursera graveolens essential oil into …

Surface-active amphiphiles find applications in a wide range of areas of industry such as
agrochemicals, personal care, and pharmaceuticals. In many of these applications …

The dermatophyte Trichophyton rubrum is responsible for most human cutaneous infections.
Its treatment is complex, mainly because there are only a few structural classes of fungal …