The variation of SARS-CoV-2 and advanced research on current vaccines

Y Jiang, Q Wu, P Song, C You - Frontiers in Medicine, 2022 - frontiersin.org
Over the past 2 years, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
caused the coronavirus disease 2019 (COVID-19) and rapidly spread worldwide. In the …

Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines

YC Bartsch, X Tong, J Kang, MJ Avendaño… - Science translational …, 2022 - science.org
The Omicron variant of SARS-CoV-2 has been shown to evade neutralizing antibodies
elicited by vaccination or infection. Despite the global spread of the Omicron variant, even …

Association of prior SARS-CoV-2 infection with risk of breakthrough infection following mRNA vaccination in Qatar

LJ Abu-Raddad, H Chemaitelly, HH Ayoub… - Jama, 2021 - jamanetwork.com
Importance The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly
understood. Objective To assess protection from SARS-CoV-2 breakthrough infection after …

Counting on COVID-19 vaccine: insights into the current strategies, progress and future challenges

R Kandimalla, P Chakraborty, J Vallamkondu… - Biomedicines, 2021 - mdpi.com
The emergence of a novel coronavirus viz., severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) in late 2019 and its subsequent substantial spread produced the …

Infectivity and immune escape of the new SARS-CoV-2 variant of interest Lambda

ML Acevedo, L Alonso-Palomares, A Bustamante… - Medrxiv, 2021 - medrxiv.org
Background The newly described SARS-CoV-2 lineage C. 37 was recently classified as a
variant of interest by the WHO (Lambda variant) based on its high circulation rates in South …

Single‐cell transcriptomic atlas reveals distinct immunological responses between COVID‐19 vaccine and natural SARS‐CoV‐2 infection

Y Wang, X Wang, LDW Luu, J Li, X Cui… - Journal of Medical …, 2022 - Wiley Online Library
To control the ongoing coronavirus disease‐2019 (COVID‐19) pandemic, CoronaVac
(Sinovac), an inactivated vaccine, has been granted emergency use authorization by many …

Antibody response to SARS-CoV-2 vaccines in people with severe obesity

Z Kara, R Akçin, AN Demir, HÖ Dinç, HE Taşkın… - Obesity Surgery, 2022 - Springer
Aim Obesity is a disease complicating the course of COVID-19 and SARS-CoV-2 vaccine
effectiveness in adults with obesity may be compromised. Our aim is to investigate the spike …

Clinical course impacts early kinetics, magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

E Pradenas, B Trinité, V Urrea, S Marfil… - Cell Reports …, 2022 - cell.com
To understand the determinants of long-term immune responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and the concurrent impact of vaccination and …

Salivary, serological, and cellular immune response to the CoronaVac vaccine in health care workers with or without previous COVID-19

MM Ortega, LT da Silva, ÉD Candido, Y Zheng… - Scientific Reports, 2022 - nature.com
We investigated the anti-SARS-CoV-2 post-vaccine response through serum and salivary
antibodies, serum antibody neutralizing activity and cellular immune response in samples …

Waning immunity to inactive SARS-CoV-2 vaccine in healthcare workers: booster required

İİ Balkan, HO Dinc, G Can, R Karaali, D Ozbey… - Irish Journal of Medical …, 2023 - Springer
Aims Despite high vaccination rates, increasing case numbers continue to be reported with
the identification of new variants of concern, and the issue of durability of the vaccine …