Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Effects of exercise‐induced ROS on the pathophysiological functions of skeletal muscle

F Wang, X Wang, Y Liu, Z Zhang - Oxidative medicine and …, 2021 - Wiley Online Library
Oxidative stress is the imbalance of the redox system in the body, which produces excessive
reactive oxygen species, leads to multiple cellular damages, and closely relates to some …

Positive aspects of oxidative stress at different levels of the human body: A review

G Jîtcă, BE Ősz, A Tero-Vescan, AP Miklos, CM Rusz… - Antioxidants, 2022 - mdpi.com
Oxidative stress is the subject of numerous studies, most of them focusing on the negative
effects exerted at both molecular and cellular levels, ignoring the possible benefits of free …

Mechanisms of myofascial pain

MS Jafri - International scholarly research notices, 2014 - Wiley Online Library
Myofascial pain syndrome is an important health problem. It affects a majority of the general
population, impairs mobility, causes pain, and reduces the overall sense of well‐being …

Identifying the structural adaptations that drive the mechanical load-induced growth of skeletal muscle: a scoping review

KW Jorgenson, SM Phillips, TA Hornberger - Cells, 2020 - mdpi.com
The maintenance of skeletal muscle mass plays a critical role in health and quality of life.
One of the most potent regulators of skeletal muscle mass is mechanical loading, and …

Exercise-induced skeletal muscle remodeling and metabolic adaptation: redox signaling and role of autophagy

E Ferraro, AM Giammarioli, S Chiandotto… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Skeletal muscle is a highly plastic tissue. Exercise evokes signaling pathways
that strongly modify myofiber metabolism and physiological and contractile properties of …

Regulation of myokine expression: Role of exercise and cellular stress

M Ost, V Coleman, J Kasch, S Klaus - Free Radical Biology and Medicine, 2016 - Elsevier
Exercise training is well known to improve physical fitness and to combat chronic diseases
and aging related disorders. Part of this is thought to be mediated by myokines, muscle …

Impairment between oxidant and antioxidant systems: short-and long-term implications for athletes' health

C Nocella, V Cammisotto, F Pigozzi, P Borrione… - Nutrients, 2019 - mdpi.com
The role of oxidative stress, an imbalance between reactive oxygen species production
(ROS) and antioxidants, has been described in several patho-physiological conditions …

[HTML][HTML] Dietary antioxidants as modifiers of physiologic adaptations to exercise

RT Mankowski, SD Anton, TW Buford… - Medicine and science …, 2015 - ncbi.nlm.nih.gov
Adaptive responses to exercise training (ET) are crucial in maintaining physiological
homeostasis and health span. Exercise-induced aerobic bioenergetic reactions in …

Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease

R Guo, EC Liong, KF So, ML Fung, GL Tipoe - Hepatobiliary & pancreatic …, 2015 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) refers to any fatty liver disease that is
not due to excessive use of alcohol. NAFLD probably results from abnormal hepatic lipid …