Structural simplification of natural products
S Wang, G Dong, C Sheng - Chemical Reviews, 2019 - ACS Publications
Natural products (NPs) are important sources of clinical drugs due to their structural diversity
and biological prevalidation. However, the structural complexity of NPs leads to synthetic …
and biological prevalidation. However, the structural complexity of NPs leads to synthetic …
Marine natural products
Covering: 2002. Previous review: Nat. Prod. Rep., 2003, 20, 1 This review covers the
literature published in 2002 for marine natural products, with 579 citations (413 for the …
literature published in 2002 for marine natural products, with 579 citations (413 for the …
Marine natural products
DJ Faulkner - Natural product reports, 2000 - pubs.rsc.org
044disk doc..044disk chapter .. Page7 Page 1 Marine natural products D. John Faulkner
Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA …
Scripps Institution of Oceanography, University of California at San Diego, La Jolla, CA …
Natural products as a foundation for drug discovery
JA Beutler - Current protocols in pharmacology, 2009 - Wiley Online Library
Natural products have provided chemical leads for the development of many drugs for
diverse indications. While most US pharmaceutical firms have reduced or eliminated their in …
diverse indications. While most US pharmaceutical firms have reduced or eliminated their in …
Copper-catalyzed coupling of amides and carbamates with vinyl halides
L Jiang, GE Job, A Klapars, SL Buchwald - Organic Letters, 2003 - ACS Publications
A general and efficient copper-catalyzed method for the amidation of vinyl bromides and
iodides has been developed. This protocol uses a combination of 5 mol% copper iodide and …
iodides has been developed. This protocol uses a combination of 5 mol% copper iodide and …
Marine natural products
Covering: 2003. Previous review: Nat. Prod. Rep., 2004, 21, 1 This review covers the
literature published in 2003 for marine natural products, with 619 citations (413 for the …
literature published in 2003 for marine natural products, with 619 citations (413 for the …
Inhibitors of V-ATPases: old and new players
M Huss, H Wieczorek - Journal of Experimental Biology, 2009 - journals.biologists.com
SUMMARY V-ATPases constitute a ubiquitous family of heteromultimeric, proton
translocating proteins. According to their localization in a multitude of eukaryotic …
translocating proteins. According to their localization in a multitude of eukaryotic …
Chemistry and biology of salicylihalamide A and related compounds
L Yet - Chemical reviews, 2003 - ACS Publications
The use of plant and marine extracts in the search for biologically active natural products
continues to be a powerful method for the identification of lead compounds for many …
continues to be a powerful method for the identification of lead compounds for many …
Deep-sea natural products
D Skropeta - Natural product reports, 2008 - pubs.rsc.org
Covering: up to the end of 2007 This review covers the 390 novel marine natural products
described to date from deep-water (> 50 m) marine fauna, with details on the source …
described to date from deep-water (> 50 m) marine fauna, with details on the source …
Synthesis of enamides related to the salicylate antitumor macrolides using copper-mediated vinylic substitution
R Shen, JA Porco - Organic letters, 2000 - ACS Publications
A new approach to the assembly of enamides is described using copper (I) carboxylate-
catalyzed substitution of vinyl iodides and amides. Modified reaction conditions have been …
catalyzed substitution of vinyl iodides and amides. Modified reaction conditions have been …