[HTML][HTML] Effects and mechanisms of N6-methyladenosine RNA methylation in environmental pollutant-induced carcinogenesis
Environmental pollution, including air pollution, plastic contamination, and heavy metal
exposure, is a pressing global issue. This crisis contributes significantly to pollution-related …
exposure, is a pressing global issue. This crisis contributes significantly to pollution-related …
[HTML][HTML] The Beak of Eukaryotic Ribosomes: Life, Work and Miracles
S Martín-Villanueva, CV Galmozzi… - …, 2024 - pmc.ncbi.nlm.nih.gov
Ribosomes are not totally globular machines. Instead, they comprise prominent structural
protrusions and a myriad of tentacle-like projections, which are frequently made up of …
protrusions and a myriad of tentacle-like projections, which are frequently made up of …
Pangenomes of human gut microbiota uncover links between genetic diversity and stress response
The genetic diversity of the gut microbiota has a central role in host health. Here, we created
pangenomes for 728 human gut prokaryotic species, quadrupling the genes of strain …
pangenomes for 728 human gut prokaryotic species, quadrupling the genes of strain …
[HTML][HTML] Dynamic protein composition of Saccharomyces cerevisiae ribosomes in response to multiple stress conditions reflects alterations in translation activity
PJ Pietras, A Wasilewska-Burczyk, K Pepłowska… - International Journal of …, 2024 - Elsevier
Ribosomes, intercellular macromolecules responsible for translation in the cell, are
composed of RNAs and proteins. While rRNA makes the scaffold of the ribosome and directs …
composed of RNAs and proteins. While rRNA makes the scaffold of the ribosome and directs …
Loss of NAT10 Reduces the Translation of Kmt5a mRNA Through ac4C Modification in Cardiomyocytes and Induces Heart Failure
T Xu, T Du, X Zhuang, X He, Y Yan, J Wu… - Journal of the …, 2024 - ahajournals.org
Background In the past decade, the biological functions of various RNA modifications in
mammals have been uncovered. N4‐acetylcytidine (ac4C), a highly conserved RNA …
mammals have been uncovered. N4‐acetylcytidine (ac4C), a highly conserved RNA …
[HTML][HTML] RiboScreenTM Technology Delivers a Ribosomal Target and a Small-Molecule Ligand for Ribosome Editing to Boost the Production Levels of Tropoelastin …
B Wimmer, J Schernthaner, G Edobor… - International Journal of …, 2024 - mdpi.com
Elastin, a key structural protein essential for the elasticity of the skin and elastogenic tissues,
degrades with age. Replenishing elastin holds promise for anti-aging cosmetics and the …
degrades with age. Replenishing elastin holds promise for anti-aging cosmetics and the …
Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation
A Papadimitriou‐Tsantarliotou, C Avgeros… - IUBMB …, 2024 - Wiley Online Library
Within the last decade, the scientific community has witnessed the importance of ferroptosis
as a novel cascade of molecular events leading to cellular decisions of death distinct from …
as a novel cascade of molecular events leading to cellular decisions of death distinct from …
Polymerase I as a Target for Treating Neurodegenerative Disorders
MS LeDoux - Biomedicines, 2024 - mdpi.com
Polymerase I (Pol I) is at the epicenter of ribosomal RNA (rRNA) synthesis. Pol I is a target
for the treatment of cancer. Given the many cellular commonalities between cancer and …
for the treatment of cancer. Given the many cellular commonalities between cancer and …
[PDF][PDF] Correction: Islam, RA; Rallis, C. Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging. Epigenomes 2023, 7, 17
23. Leppek, K.; Fujii, K.; Quade, N.; Susanto, TT; Boehringer, D.; Lenarcic, T.; Xue, S.;
Genuth, NR; Ban, N.; Barna, M. Gene-and Species-Specific Hox MRNA Translation by …
Genuth, NR; Ban, N.; Barna, M. Gene-and Species-Specific Hox MRNA Translation by …