Deleterious mutations decrease reproductive fitness and are ubiquitous in genomes. Given
that many organisms face ongoing threats of extinction, there is interest in elucidating the …

Climate change is a threat to biodiversity. One way that this threat manifests is through
pronounced shifts in the geographical range of species over time. To predict these shifts …

Human activity has caused dramatic population declines in many wild species. The resulting
bottlenecks have a profound impact on the genetic makeup of a species with unknown …

Recent theory and empirical evidence have provided new insights regarding how
evolutionary forces interact to shape adaptation at stable and transient range margins …

We urgently need to predict species responses to climate change to minimize future
biodiversity loss and ensure we do not waste limited resources on ineffective conservation …

Understanding the movement of species' ranges is a classic ecological problem that takes
on urgency in this era of global change. Historically treated as a purely ecological process …

Species' range limits are ubiquitous. This suggests that the evolution of the ecological niche
is constrained in general and at the edges of distributions in particular. While there may be …

The genetic swamping hypothesis proposes that gene flow from central to peripheral
populations inhibits local adaptation and is one of the most widely recognized explanations …

Motivation Theory describing biodiversity gradients has focused on species richness with
less conceptual synthesis outlining expectations for intraspecific diversity gradients, that is …

New mutations provide the raw material for evolution and adaptation. The distribution of
fitness effects (DFE) describes the spectrum of effects of new mutations that can occur along …