N Zhang, AS Ng, S Cai, Q Li, L Yang, D Kerr - The lancet oncology, 2021 - thelancet.com
Epithelial–mesenchymal transition (EMT) is a process during which cells lose their epithelial characteristics, for instance apical–basal cell polarity and cell–cell contact, and gain …
The cytoskeleton of animal cells is one of the most complicated and functionally versatile structures, involved in processes such as endocytosis, cell division, intra-cellular transport …
The cytoskeleton plays an integral role in maintaining the integrity of epithelial cells. Epithelial cells primarily employ cytokeratin in their cytoskeleton, whereas mesenchymal …
K Strouhalova, M Přechová, A Gandalovičová… - Cancers, 2020 - mdpi.com
Intermediate filaments constitute the third component of the cellular skeleton. Unlike actin and microtubule cytoskeletons, the intermediate filaments are composed of a wide variety of …
Vimentin, an abundant cytoplasmic intermediate filament protein, is recognized for its important role in stabilizing intracellular structure. Vimentin has been recognized for its …
M Kapoor, S Chinnathambi - Journal of Neuroinflammation, 2023 - Springer
Microtubule-associated protein, Tau has been implicated in Alzheimer's disease for its detachment from microtubules and formation of insoluble intracellular aggregates within the …
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal functions, and therefore in basic cellular processes such as cell division and migration …
LS Coelho-Rato, S Parvanian, MK Modi… - Trends in Cell Biology, 2024 - cell.com
As a member of the large family of intermediate filaments (IFs), vimentin has emerged as a highly dynamic and versatile cytoskeletal protein involved in many key processes of wound …
Vimentin expression contributes to cellular mechanoprotection and is a widely recognized marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how …