Composites of electrospun‐fibers and hydrogels: A potential solution to current challenges in biological and biomedical field

S Xu, L Deng, J Zhang, L Yin… - Journal of Biomedical …, 2016 - Wiley Online Library
With increasingly rigorous requirements for biomaterials, the design and fabrication of novel
materials with smart functions are urgently needed. The fabrication of composite materials …

Cell microarray technologies for high-throughput cell-based biosensors

HJ Hong, WS Koom, WG Koh - Sensors, 2017 - mdpi.com
Due to the recent demand for high-throughput cellular assays, a lot of efforts have been
made on miniaturization of cell-based biosensors by preparing cell microarrays. Various …

Facile preparation of micropatterned thermoplastic surface for wearable capacitive sensor

Y Zhang, M Gao, C Gao, G Zheng, Y Ji, K Dai… - … Science and Technology, 2023 - Elsevier
Highly sensitive and flexible capacitive sensors are in great demand for wearable
electronics, which can be achieved by preparing micropatterns on their dielectric layer …

Nanofibers regulate single bone marrow stem cell osteogenesis via FAK/RhoA/YAP1 pathway

B Chang, C Ma, X Liu - ACS applied materials & interfaces, 2018 - ACS Publications
Understanding cell-material interactions is a prerequisite for the development of bio-inspired
materials for tissue regeneration. While nanofibrous biomaterials have been widely used in …

Integration of a fiber-based cell culture and biosensing system for monitoring of multiple protein markers secreted from stem cells

J Ko, J Ham, H Lee, K Lee, WG Koh - Biosensors and Bioelectronics, 2021 - Elsevier
We propose a new platform that can integrate three-dimensional cell culture scaffold and a
surface-enhanced Raman spectroscopy (SERS)-based biosensor by stacking them to form a …

Hydrogel micropattern-incorporated fibrous scaffolds capable of sequential growth factor delivery for enhanced osteogenesis of hMSCs

HJ Lee, WG Koh - ACS Applied Materials & Interfaces, 2014 - ACS Publications
In this study, we developed multi-functional biomimetic tissue engineered scaffolds that are
capable of controlling the spatial locations of stem cells and releasing multiple growth …

Hydrogel-framed nanofiber matrix integrated with a microfluidic device for fluorescence detection of matrix metalloproteinases-9

SW Han, WG Koh - Analytical chemistry, 2016 - ACS Publications
Matrix metalloproteinases (MMPs) play a pivotal role in regulating the composition of the
extracellular matrix and have a critical role in vascular disease, cancer progression, and …

Functional polymers in protein detection platforms: optical, electrochemical, electrical, mass-sensitive, and magnetic biosensors

J Hahm - Sensors, 2011 - mdpi.com
The rapidly growing field of proteomics and related applied sectors in the life sciences
demands convenient methodologies for detecting and measuring the levels of specific …

A three-dimensional co-culture of HepG2 spheroids and fibroblasts using double-layered fibrous scaffolds incorporated with hydrogel micropatterns

HW Lee, YM Kook, HJ Lee, H Park, WG Koh - RSC Advances, 2014 - pubs.rsc.org
We developed a novel methodology of constructing a three-dimensional (3D) heterotypic co-
culture system based on double-layered fibrous scaffolds incorporated with hydrogel …

Fabrication of hydrogel-micropatterned nanofibers for highly sensitive microarray-based immunosensors having additional enzyme-based sensing capability

Y Lee, HJ Lee, KJ Son, WG Koh - Journal of Materials Chemistry, 2011 - pubs.rsc.org
Nanofiber-based protein microarrays were fabricated through a combination of
electrospinning and hydrogel lithography. Electrospinning generated polystyrene (PS)/poly …