In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …

Nuclear magnetic resonance (NMR) spectroscopy is a well-established method for
analyzing protein structure, interaction, and dynamics at atomic resolution and in various …

NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

We review the challenges and opportunities for biosensor research in North America aimed
to accelerate translational research. We call for platform approaches based on: i) tools that …

Unsaturated fatty acids (UFA) play a crucial role in central cellular processes in animals,
including membrane function, development, and disease. Disruptions in UFA homeostasis …

Understanding how the crowded and complex cellular milieu affects protein stability and
dynamics has only recently become possible by using techniques such as in-cell nuclear …

Glycan‐mediated molecular recognition events are essential for life. NMR is widely used to
monitor glycan binding to lectins in solution using isolated glycans and lectins. In this …

Methionine sulfoxidation is a posttranslational modification (PTM) playing important roles in
cell signaling. Herein, we present ptm, an R package for the study of this modification …

In-cell NMR spectroscopy has emerged as a powerful tool to evaluate protein conformations
and dynamics in the native environment of live cells. Here we extend these studies to a …

One requirement for the survival and reproduction of living organisms is the ability to receive
external stimuli and then respond appropriately. It is increasingly understood that …