Bioactive compounds, health benefits and functional food products of sea buckthorn: A review

K Wang, Z Xu, X Liao - Critical Reviews in Food Science and …, 2022 - Taylor & Francis
Sea buckthorn (Hippophae rhamnoides L.), which has been categorized as a “medicine
food homology” fruit by China's National Health Commission for both nutritional and …

Osteopontin, a bridge links osteoarthritis and osteoporosis

RJ Bai, YS Li, FJ Zhang - Frontiers in Endocrinology, 2022 - frontiersin.org
Osteoarthritis (OA) is the most prevalent joint disease characterized by degradation of
articular cartilage, inflammation, and changes in periarticular and subchondral bone of …

[HTML][HTML] Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy

S Xue, X Zhou, W Sang, C Wang, H Lu, Y Xu, Y Zhong… - Bioactive materials, 2021 - Elsevier
Cartilage-targeting delivery of therapeutic agents is still an effective strategy for osteoarthritis
(OA) therapy. Recently, scavenging for reactive oxygen species (ROS) and activating …

Oleanolic acid, a small-molecule natural product, inhibits ECM degeneration in osteoarthritis by regulating the Hippo/YAP and Wnt/β-catenin pathways

T Ma, H Ruan, L Lv, C Wei, Y Yu, L Jia, X Song… - Food & Function, 2023 - pubs.rsc.org
Over the past few decades, osteoarthritis (OA) has been a major health problem worldwide.
It is urgent to develop new, effective, and safe drugs to treat OA. There are many pentacyclic …

Brij® integrated bilosomes for improving the transdermal delivery of niflumic acid for effective treatment of osteoarthritis: In vitro characterization, ex vivo permeability …

MA Abdelbari, AA El-Gazar, AA Abdelbary… - International Journal of …, 2023 - Elsevier
Bilosomes are innovative vesicular carriers containing bile salt with a non-ionic surfactant.
Being highly flexible, bilosomes can squeeze themselves through the skin carrying the drug …

Isorhamnetin attenuates high-fat and high-fructose diet induced cognitive impairments and neuroinflammation by mediating MAPK and NFκB signaling pathways

A Mulati, X Zhang, T Zhao, B Ren, L Wang, X Liu… - Food & Function, 2021 - pubs.rsc.org
Isorhamnetin (ISO), a flavonoid compound isolated from sea-buckthorn (Hippophae
rhamnoides L.) fruit, has anti-inflammatory effects. However, the effects of ISO on …

Study on The Anti-Inflammatory Effects of Callicarpa nudiflora Based on The Spectrum–Effect Relationship

Y Li, Y Yang, X Kang, X Li, Y Wu, J Xiao, Y Ye… - Frontiers in …, 2022 - frontiersin.org
Callicarpa nudiflora (C. nudiflora) is widely used to treat inflammation-related diseases in
China. C. nudiflora mainly contains phenylethanol glycosides, flavonoids, triterpenes …

Bilobalide exerts anti-inflammatory effects on chondrocytes through the AMPK/SIRT1/mTOR pathway to attenuate ACLT-induced post-traumatic osteoarthritis in rats

T Ma, L Lv, Y Yu, L Jia, X Song, XY Xu, T Li… - Frontiers in …, 2022 - frontiersin.org
Although osteoarthritis (OA) significantly affects the quality of life of the elderly, there is still
no effective treatment strategy. The standardized Ginkgo biloba L. extract preparation has …

Improving phenolic compound extraction from Arnica montana flowers through multivariate optimization of heat and ultrasound-assisted methods

P Garcia-Oliveira, F Chamorro, J Simal-Gandara… - Sustainable Chemistry …, 2024 - Elsevier
This study aimed to optimize phenolic compound extraction from Arnica montana (AM) L.
flowers, comparing heat-and ultrasound-assisted extraction (HAE and UAE) through a …

Osteopontin: a bone-derived protein involved in rheumatoid arthritis and osteoarthritis immunopathology

BT Martín-Márquez, F Sandoval-García… - Biomolecules, 2023 - mdpi.com
Osteopontin (OPN) is a bone-derived phosphoglycoprotein related to physiological and
pathological mechanisms that nowadays has gained relevance due to its role in the immune …