UtilisingGalleria mellonella larvae for studying in vivo activity of conventional and novel antimicrobial agents

M Piatek, G Sheehan, K Kavanagh - Pathogens and Disease, 2020 - academic.oup.com
The immune response of insects displays many structural and functional similarities to the
innate immune response of mammals. As a result of these conserved features, insects may …

Cryptococcus gattii: where do we go from here?

J Harris, S Lockhart, T Chiller - Sabouraudia, 2012 - academic.oup.com
Infections caused by the emerging pathogen Cryptococcus gattii are increasing in frequency
in North America. During the past decade, interest in the pathogen has continued to grow …

Identification of T helper (Th)1- and Th2-associated antigens of Cryptococcus neoformans in a murine model of pulmonary infection

C Firacative, AE Gressler, K Schubert, B Schulze… - Scientific reports, 2018 - nature.com
Cryptococcosis, caused by Cryptococcus neoformans, has been demonstrated to be
controlled by T helper (Th) 1 cells while Th2 cells are associated with fungal growth and …

The role of oxidative and nitrosative bursts caused by azoles and amphotericin B against the fungal pathogen Cryptococcus gattii

GF Ferreira, LM Baltazar, JRA Santos… - Journal of …, 2013 - academic.oup.com
Objectives Although the most accepted mechanisms of action of amphotericin B and azoles
are related to ergosterol, it is possible that these drugs have other effects on the fungal cell …

Immunotherapy against systemic fungal infections based on monoclonal antibodies

C Boniche, SA Rossi, B Kischkel, F Vieira Barbalho… - Journal of Fungi, 2020 - mdpi.com
The increasing incidence in systemic fungal infections in humans has increased focus for
the development of fungal vaccines and use of monoclonal antibodies. Invasive mycoses …

Immunoproteomic Approach of Extracellular Antigens From Paracoccidioides Species Reveals Exclusive B-Cell Epitopes

ALE Moreira, MAP Oliveira, LOHS Silva… - Frontiers in …, 2020 - frontiersin.org
Fungi of the Paracoccidioides genus are the etiological agents of paracoccidioidomycosis
(PCM), a systemic mycosis restricted to the countries of Latin America. Currently, the …

Fungal proteomics: from identification to function

S Doyle - FEMS microbiology letters, 2011 - academic.oup.com
Some fungi cause disease in humans and plants, while others have demonstrable potential
for the control of insect pests. In addition, fungi are also a rich reservoir of therapeutic …

Genotypes of Cryptococcus neoformans and Cryptococcus gattii as agents of endemic cryptococcosis in Teresina, Piauí (northeastern Brazil)

LMS Martins, B Wanke, MS Lazéra, L Trilles… - Memorias do Instituto …, 2011 - SciELO Brasil
Throughout Brazil, Cryptococcus neoformans is the cause of cryptococcosis, whereas
Cryptococcus gattii is endemic to the northern and northeastern states. In this study, the …

Identification of disease-associated cryptococcal proteins reactive with serum IgG from cryptococcal meningitis patients

AE Gressler, D Volke, C Firacative… - Frontiers in …, 2021 - frontiersin.org
Cryptococcus neoformans, an opportunistic fungal pathogen ubiquitously present in the
environment, causes cryptococcal meningitis (CM) mainly in immunocompromised patients …

Immunoproteomics and Immunoinformatics Analysis of Cryptococcus Gattii: Novel Candidate Antigens for Diagnosis

LMS Martins, HM Andrade, MH Vainstein… - Future …, 2013 - Taylor & Francis
Aim: To identify immunoreactive proteins of Cryptococcus gattii genotype VGII and their B-
cell epitopes. Materials & methods: We combined 2D gel electrophoresis, immunoblotting …