Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Chimeric antigen receptor (CAR)-T cell therapy represents a landmark advance in
personalized cancer treatment. CAR-T strategy generally engineers T cells from a specific …

Despite its clinical success, chimeric antigen receptor T (CAR T)‐cell immunotherapy
remains limited in solid tumors, owing to the harsh physical barriers and …

Noncovalent interactions between cells and environmental cues have been recognized as
fundamental physiological interactions that regulate cell behavior. However, the effects of …

Bioorthogonal chemistry reactions occur in physiological conditions without interfering with
normal physiological processes. Through metabolic engineering, bioorthogonal groups can …

Nanoparticle-based systems are extensively investigated for drug delivery. Among others,
with superior biocompatibility and enhanced targeting capacity, albumin appears to be a …

Simple Summary While most cancer immunotherapies have focused on CD8+ T cells as the
main drivers of antitumor immunity, increasing evidence indicates that CD4+ T cells also …

In the past decade, the emergence of chimeric antigen receptor (CAR) T-cell therapy has led
to a cellular immunotherapy revolution against various cancers. Although CAR-T cell …

Natural killer (NK) cell‐based immunotherapy holds prominent potential for cancer
treatment. However, its application in solid tumors is limited by a rapid decline in viability …

Adoptive transfer of naturally occurring or genetically engineered T cells is an effective
treatment for certain haematological malignancies, such as non-Hodgkin lymphoma and …