Inflammation response of epithelial mucosa to chemo-radiotherapy cytotoxic effects leads to
mucositis, a painful side effect of antineoplastic treatments. About 40% of the patients treated …

Oral mucositis is a common complication of cancer treatment that may negatively impact the
patient's cancer treatment outcome. Despite its frequency and consequences, the lack of …

FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin), a 5-fluorouracil (5-FU)-based
chemotherapy regimen, is one of most common therapeutic regimens for colorectal cancer …

Glutamine is a major dietary amino acid that is both a fuel and nitrogen donor for healing
tissues damaged by chemotherapy and radiation. Evidence supports the benefit of oral …

Cancer, a major world public health problem, is associated with chemotherapy treatments
whose administration leads to secondary concerns, such as oral mucositis (OM). The OM …

Background Considerable progress has been made in our understanding of the biological
basis for cancer therapy-induced mucosal barrier injury (mucositis). The last formal review of …

Purpose Diarrhea is one of the dose limiting toxicity of irinotecan. SN-38 is main irinotecan
metabolite responsible for diarrhea development, which is excreted in glucuronidated form …

Chemotherapy-induced diarrhea (CID) is a common and often severe side effect
experienced by colorectal cancer (CRC) patients during their treatment. As chemotherapy …

Purpose: Cancer treatment is one of the most challenging diseases in the present era.
Among a few modalities for cancer therapy, radiotherapy plays a pivotal role in more than …

Adjuvant 5-fluorouracil (5-FU)-based chemotherapy, including FOLFOX (5-FU, leucovorin,
and oxaliplatin), is recommended for colorectal cancer. However, intestinal mucositis …