FGF/FGFR signaling in health and disease

Y Xie, N Su, J Yang, Q Tan, S Huang, M Jin… - Signal transduction and …, 2020 - nature.com
Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Pediatric low-grade glioma in the era of molecular diagnostics

S Ryall, U Tabori, C Hawkins - Acta neuropathologica communications, 2020 - Springer
Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation

DW Ellison, C Hawkins, DTW Jones… - Acta …, 2019 - Springer
Diffuse gliomas occur at all ages, but their incidence is highest among older adults [7]. They
have astrocytic or oligodendroglial morphologies and are represented across WHO grades II …

Pediatric gliomas: current concepts on diagnosis, biology, and clinical management

D Sturm, SM Pfister, DTW Jones - Journal of Clinical Oncology, 2017 - ascopubs.org
Gliomas are the most common CNS tumors in children and adolescents, and they show an
extremely broad range of clinical behavior. The majority of pediatric gliomas present as …

Pan-neuroblastoma analysis reveals age-and signature-associated driver alterations

SW Brady, Y Liu, X Ma, AM Gout, K Hagiwara… - Nature …, 2020 - nature.com
Neuroblastoma is a pediatric malignancy with heterogeneous clinical outcomes. To better
understand neuroblastoma pathogenesis, here we analyze whole-genome, whole-exome …

Low-grade developmental and epilepsy associated brain tumors: a critical update 2020

RJ Slegers, I Blumcke - Acta neuropathologica communications, 2020 - Springer
Brain tumors represent the second most frequent etiology in patients with focal seizure onset
before 18 years of age and submitted to epilepsy surgery. Hence, this category of brain …

The genetic landscape of ganglioglioma

M Pekmezci, JE Villanueva-Meyer, B Goode… - Acta neuropathologica …, 2018 - Springer
Ganglioglioma is the most common epilepsy-associated neoplasm that accounts for
approximately 2% of all primary brain tumors. While a subset of gangliogliomas are known …

Pediatric low-grade gliomas: next biologically driven steps

DTW Jones, MW Kieran, E Bouffet… - Neuro …, 2018 - academic.oup.com
Despite the fact that they are not typically life-threatening, low-grade gliomas (LGGs) remain
a significant clinical challenge in pediatric neuro-oncology due to comorbidities associated …

Pediatric low-grade gliomas: implications of the biologic era

RJ Packer, S Pfister, E Bouffet, R Avery… - Neuro …, 2017 - academic.oup.com
For the past decade, it has been recognized that pediatric low-grade gliomas (LGGs) and
glial-neuronal tumors carry distinct molecular alterations with resultant aberrant intracellular …

Management of pediatric low-grade glioma

P De Blank, P Bandopadhayay… - Current opinion in …, 2019 - journals.lww.com
Management of pediatric low-grade glioma : Current Opinion in Pediatrics Management of
pediatric low-grade glioma : Current Opinion in Pediatrics Log in or Register Subscribe to …