The recent success of PD-1 and PD-L1 blockade in cancer therapy illustrates the important
role of the PD-1/PD-L1 pathway in the regulation of antitumor immune responses. However …

The immune system must work in an orchestrated way to achieve an optimal response upon
detection of antigens. The cells comprising the immune response are traditionally divided …

Group 2 Innate lymphoid cells (ILC2) contribute significantly to allergic inflammation.
However, the role of microbiota on ILC2s remains to be unraveled. Here we show that short …

Allergic asthma is a complex and chronic inflammatory disorder that is associated with
airway hyperreactivity (AHR) and driven by Th2 cytokine secretion. Type 2 innate lymphoid …

Background NK cells seem to be mainly involved in COVID-19 pneumonia. Little is known
about NKT cells which represent a bridge between innate and adaptive immunity. Methods …

The prevalence of asthma and airway hyperreactivity (AHR) is increasing at an alarming
rate. Group 2 innate lymphoid cells (ILC2s) are copious producers of type 2 cytokines, which …

Background Allergic asthma is a prevalent inflammatory disease of the airways caused by
dysregulated immune balance in the lungs with incompletely understood pathogenesis. The …

Group 2 innate lymphoid cells (ILC2s) can initiate pathologic inflammation in allergic asthma
by secreting copious amounts of type 2 cytokines, promoting lung eosinophilia and airway …

The mammalian immune system has evolved the capacity to detect and destroy tumor cells.
Tumors utilize multiple strategies to evade host immune surveillance, including the induction …

Influenza A viruses (IAVs) cause respiratory illness of varying severity based on the virus
strains, host predisposition and pre-existing immunity. Ultimately, outcome and recovery …