Growing evidence demonstrates a continuous interaction between the immune system, the
nerve and the muscle in neuromuscular disorders of different pathogenetic origins, such as …

The immune system plays an essential role in tissue repair and regeneration. Regardless of
innate or adaptive immune responses, immunosuppressive strategies such as macrophage …

Ferroptosis, characterized by iron accumulation and lipid peroxidation, leads to cell death.
Growing evidence suggests the involvement of ferroptosis in sarcopenia. However, the …

Growing evidence demonstrates a continuous interaction between the immune system and
the skeletal muscle in inflammatory diseases of different pathogenetic origins, in dystrophic …

Many neuromuscular disease entities possess a significant disease burden and therapeutic
options remain limited. Innovative human preclinical models may help to uncover relevant …

DNA vaccines elicit antibody, T helper cell responses and CD8+ T cell responses. Currently,
little is known about the mechanism that DNA vaccines employ to induce adaptive immune …

Inclusion body myositis (IBM) is the most prevalent inflammatory muscle disease in older
adults with no effective therapy available. In contrast to other inflammatory myopathies such …

Muscular dystrophies (MDs) are genetically heterogeneous diseases characterized by
primary skeletal muscle atrophy. The collapse of muscle structure and irreversible …

Pathological and inflammatory events in muscle after the injection of snake venoms vary in
different regions of the affected tissue and at different time intervals. In order to study such …

Abstract Background Ochratoxin A (OTA), a globally abundant and extremely hazardous
pollutant, is a significant source of contamination in aquafeeds and is responsible for severe …