The sympathetic nervous system in development and disease

E Scott-Solomon, E Boehm, R Kuruvilla - Nature Reviews …, 2021 - nature.com
The sympathetic nervous system prepares the body for 'fight or flight'responses and
maintains homeostasis during daily activities such as exercise, eating a meal or regulation …

Metabolic functions of FABPs—mechanisms and therapeutic implications

GS Hotamisligil, DA Bernlohr - Nature Reviews Endocrinology, 2015 - nature.com
Intracellular and extracellular interactions with proteins enables the functional and
mechanistic diversity of lipids. Fatty acid-binding proteins (FABPs) were originally described …

An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders

NJ Ashton, A Hye, AP Rajkumar, A Leuzy… - Nature Reviews …, 2020 - nature.com
Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology
at the earliest stage of some neurodegenerative disorders, but do not have the scalability …

Satellite glial cells promote regenerative growth in sensory neurons

O Avraham, PY Deng, S Jones, R Kuruvilla… - Nature …, 2020 - nature.com
Peripheral sensory neurons regenerate their axon after nerve injury to enable functional
recovery. Intrinsic mechanisms operating in sensory neurons are known to regulate nerve …

The glial nature of embryonic and adult neural stem cells

A Kriegstein, A Alvarez-Buylla - Annual review of neuroscience, 2009 - annualreviews.org
Glial cells were long considered end products of neural differentiation, specialized
supportive cells with an origin very different from that of neurons. New studies have shown …

eIF2B activator prevents neurological defects caused by a chronic integrated stress response

YL Wong, L LeBon, AM Basso, KL Kohlhaas, AL Nikkel… - Elife, 2019 - elifesciences.org
The integrated stress response (ISR) attenuates the rate of protein synthesis while inducing
expression of stress proteins in cells. Various insults activate kinases that phosphorylate the …

The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism

A Chmurzyńska - Journal of applied genetics, 2006 - Springer
Fatty acid-binding proteins (FABPs) are members of the superfamily of lipid-binding proteins
(LBP). So far 9 different FABPs, with tissue-specific distribution, have been identified: L …

Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage

P Malatesta, E Hartfuss, M Götz - Development, 2000 - journals.biologists.com
The developing central nervous system of vertebrates contains an abundant cell type
designated radial glial cells. These cells are known as guiding cables for migrating neurons …

The transcription factor Sox10 is a key regulator of peripheral glial development

S Britsch, DE Goerich, D Riethmacher… - Genes & …, 2001 - genesdev.cshlp.org
The molecular mechanisms that determine glial cell fate in the vertebrate nervous system
have not been elucidated. Peripheral glial cells differentiate from pluripotent neural crest …

Radial glia serve as neuronal progenitors in all regions of the central nervous system

TE Anthony, C Klein, G Fishell, N Heintz - Neuron, 2004 - cell.com
Radial glial cells function during CNS development as neural progenitors, although their
precise contribution to neurogenesis remains controversial. Recent work has argued that …