S-Adenosyl-l-Homocysteine Exhibits Potential Antiviral Activity Against Dengue Virus Serotype-3 (DENV-3) in Bangladesh: A Viroinformatics-Based Approach
Dengue outbreak is one of the concerning issues in Bangladesh due to the annual outbreak
with the alarming number of death and infection. However, there is no effective antiviral drug …
with the alarming number of death and infection. However, there is no effective antiviral drug …
[HTML][HTML] Computational identification of putative common genomic drug and vaccine targets in Mycoplasma genitalium
Mycoplasma genitalium is an obligate intracellular bacterium that is responsible for several
sexually transmitted infections, including non-gonococcal urethritis in men and several …
sexually transmitted infections, including non-gonococcal urethritis in men and several …
[HTML][HTML] Subtractive genomics approach towards the identification of novel therapeutic targets against human Bartonella bacilliformis
Bartonella bacilliformis, a causative agent of Bartonellosis or Carrión's disease, has become
resistant to antibacterial agents. To suggest effective novel drug targets, a comprehensive in …
resistant to antibacterial agents. To suggest effective novel drug targets, a comprehensive in …
Comparative Proteomics and Genome-Wide Druggability Analyses Prioritized Promising Therapeutic Targets against Drug-Resistant Leishmania tropica
Leishmania tropica is a tropical parasite causing cutaneous leishmaniasis (CL) in humans.
Leishmaniasis is a serious public health threat, affecting an estimated 350 million people in …
Leishmaniasis is a serious public health threat, affecting an estimated 350 million people in …
Computational Guided Drug Targets Identification against Extended-Spectrum Beta-Lactamase-Producing Multi-Drug Resistant Uropathogenic Escherichia coli
H Kaur, V Modgil, N Chaudhary, B Mohan, N Taneja - Biomedicines, 2023 - mdpi.com
Urinary tract infections (UTIs) are one of the most frequent bacterial infections in the world,
both in the hospital and community settings. Uropathogenic Escherichia coli (UPEC) are the …
both in the hospital and community settings. Uropathogenic Escherichia coli (UPEC) are the …
Subtractive genomics and molecular docking approach to identify drug targets against Stenotrophomonas maltophilia
Stenotrophomonas maltophilia is a multidrug resistant pathogen associated with high
mortality and morbidity in patients having compromised immunity. The efflux systems of S …
mortality and morbidity in patients having compromised immunity. The efflux systems of S …
[HTML][HTML] In silico identification and characterization of promising drug targets in highly virulent uropathogenic Escherichia coli strain CFT073 by protein-protein …
Urinary tract infections (UTIs) are one of the commonest bacterial infections worldwide. The
most common etiological agent is uropathogenic Escherichia coli. The occurrence of high …
most common etiological agent is uropathogenic Escherichia coli. The occurrence of high …
Subtractive Proteomics and Reverse-Vaccinology Approaches for Novel Drug Target Identification and Chimeric Vaccine Development against Bartonella henselae …
S Rahman, CC Chiou, S Ahmad, ZU Islam, T Tanaka… - Bioengineering, 2024 - mdpi.com
Bartonella henselae is a Gram-negative bacterium causing a variety of clinical symptoms,
ranging from cat-scratch disease to severe systemic infections, and it is primarily transmitted …
ranging from cat-scratch disease to severe systemic infections, and it is primarily transmitted …
Subtractive genomics study for the identification of therapeutic targets against Cronobacter sakazakii: A threat to infants
Cronobacter sakazakii is an opportunistic pathogen that has been associated with severe
infection in neonates such as necrotizing enterocolitis (NEC), neonatal meningitis, and …
infection in neonates such as necrotizing enterocolitis (NEC), neonatal meningitis, and …
[HTML][HTML] Subtractive genomics study of Xanthomonas oryzae pv. Oryzae reveals repurposable drug candidate for the treatment of bacterial leaf blight in rice
Background Xanthomonas oryzae pv. oryzae is a plant pathogen responsible for causing
one of the most severe bacterial diseases in rice, known as bacterial leaf blight that poses a …
one of the most severe bacterial diseases in rice, known as bacterial leaf blight that poses a …