The aldo-keto reductase (AKR) superfamily comprises enzymes that catalyze redox
transformations involved in biosynthesis, intermediary metabolism, and detoxification …

Several aldo–keto reductase (AKR) enzymes from subfamilies 1B and 1C show
retinaldehyde reductase activity, having low K m and k cat values. Only AKR1B10 and 1B12 …

A human member of the aldo–keto reductase (AKR) superfamily, AKR1B10, was identified
as a biomarker of lung cancer, exhibiting high sequence identity with human aldose …

Farnesol (FOH) and geranylgeraniol (GGOH) with multiple biological actions are produced
from the mevalonate pathway, and catabolized into farnesoic acid and geranylgeranoic acid …

Aldo-keto reductase (AKR) 1C15, a member of the AKR superfamily, was recently identified
and cloned, and reported to alleviate oxidative stress in endothelial cells in rodent lungs …

Human AKR (aldo–keto reductase) 1C proteins (AKR1C1–AKR1C4) exhibit relevant activity
with steroids, regulating hormone signalling at the pre-receptor level. In the present study …

Most members of the aldo-keto reductase (AKR) 1 C subfamily are hydroxysteroid
dehydrogenases (HSDs). Similarly to humans, four genes for AKR1C proteins (AKR1C1 …

Purpose: We studied whether the accumulation of advanced lipoxidation end-products
(ALEs) in the diabetic retina is linked to the impairment of lipid aldehyde detoxification …

Kinetically controlled and organocatalytic syn-selective transfer hydrogenation has been
successfully demonstrated for the reduction of the enone functional group of various …

A recent rat genomic sequencing predicts a gene Akr1b10 that encodes a protein with 83%
sequence similarity to human aldo–keto reductase (AKR) 1B10. In this study, we isolated the …