Cationic pullulan nanogel as a safe and effective nasal vaccine delivery system for respiratory infectious diseases

R Nakahashi-Ouchida, Y Yuki… - Human vaccines & …, 2018 - Taylor & Francis
The mucosal surfaces of the respiratory and gastrointestinal tracts are continuously exposed
to countless beneficial and pathologic antigens. These mucosal surfaces are thus equipped …

Burden of illness associated with pneumococcal infections in Japan-a targeted literature review

A Igarashi, M Ueyama, K Idehara… - Journal of Market Access …, 2022 - Taylor & Francis
ABSTRACT Introduction Pneumococcal diseases (PDs) are among the leading causes of
mortality and morbidity worldwide. However, the evidence on epidemiology, health …

[HTML][HTML] Effects of PCV10 and PCV13 on pneumococcal serotype 6C disease, carriage, and antimicrobial resistance

LR Grant, G Hanquet, IT Sepúlveda-Pachón… - Vaccine, 2024 - Elsevier
Background The cross-protection of pneumococcal conjugate vaccines (PCV) against
serotype 6C is not clearly documented, although 6C represents a substantial burden of …

Serotype replacement in adult pneumococcal pneumonia after the introduction of seven-valent pneumococcal conjugate vaccines for children in Japan: a systematic …

S Katoh, M Suzuki, K Ariyoshi… - Japanese journal of …, 2017 - jstage.jst.go.jp
Streptococcus pneumoniae is the major causative agent for adult pneumonia. Following the
introduction of pneumococcal conjugate vaccines (PCV) for children, serotype replacement …

Strategies for pneumococcal vaccination in older adults in the coming era

K Nakashima, W Fukushima - Human Vaccines & …, 2024 - Taylor & Francis
Pneumonia, predominantly caused by Streptococcus pneumoniae, remains a leading cause
of global mortality. The 23-valent Pneumococcal polysaccharide vaccine (PPSV23) and …

Serotype distribution of Streptococcus pneumoniae isolated from adult respiratory tract infections in nationwide Japanese surveillances from 2006 to 2014

H Shoji, M Maeda, T Takuma, Y Niki - Journal of infection and …, 2017 - Elsevier
Background and objective Reports on the efficacy of pneumococcal conjugate vaccines
(PCVs) have been received from many countries. However, in countries where the 7-valent …

Defining the mechanisms underlying reduced immunity to Streptococcus pneumonia with age

M Goncalves - 2018 - etheses.bham.ac.uk
This thesis tested the hypothesis that immunosenescence contributes to reduced immunity
to\(Streptococcus\)\(pneumoniae\). The effect of age on neutrophil and monocyte responses …