Natural products have been a rich source of compounds for drug discovery. However, their
use has diminished in the past two decades, in part because of technical barriers to …

Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

Microorganisms are known as important sources of natural compounds that have been
studied and applied for different purposes in distinct areas. Specifically, in the …

Genomic sequence data have revealed the presence of a large fraction of putatively silent
biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary …

Covering: up to 2020 The National Cancer Institute of the United States (NCI) has initiated a
Cancer Moonshot program entitled the NCI Program for Natural Product Discovery. As part …

Current evidence shows that herbal medicines could be beneficial for the treatment of
various diseases. However, the complexities present in chemical compositions of herbal …

Covering: up to 2018 With contributions from the global natural product (NP) research
community, and continuing the Raw Data Initiative, this review collects a comprehensive …

Covering: 2012 to 2014. Previous review: Nat. Prod. Rep., 2012, 29, 1382 The present
review discusses the isolation, structure determination, synthesis, biosynthesis and …

Coumarin and its derivatives have significantly attracted the attention of medicinal chemists
and chemical biologists due to their huge range of biological, and in particular …

The increase in the life expectancy average has led to a growing elderly population, thus
leading to a prevalence of neurodegenerative disorders, such as Parkinson's disease (PD) …