The gastrointestinal (GI) tract is home to a complex and dynamic community of
microorganisms, comprising bacteria, archaea, viruses, yeast, and fungi. It is widely …

Metabolic reprogramming has been considered a core hallmark of cancer, in which
excessive accumulation of lipids promote cancer initiation, progression and metastasis …

Esophageal cancer (EC) is a common malignant tumor of the upper digestive tract. The
microbiota in the digestive tract epithelium comprises a large number of microorganisms that …

Simple Summary Recently, the interactions between microbiota and the host have been
reported to induce the onset and progression of human cancer via epithelial–mesenchymal …

Aims: Dietary habits are reported to be associated with Barrett's esophagus (BE) risk;
however, whether there is a causal relationship remains controversial. Here, we …

Obesity is a known risk factor for the development of gastroesophageal reflux disease
(GERD), Barrett's Esophagus (BE) and the progression to esophageal adenocarcinoma. The …

Background The risk of esophageal adenocarcinoma (EAC) is associated with gastro‐
esophageal reflux disease (GERD) and obesity. Lipid metabolism‐targeted therapies …

Both obesity and esophageal adenocarcinoma (EAC) rates have increased sharply in the
United States and Western Europe in recent years. EAC is a classic example of obesity …

Background & Aims This review was developed to provide a thorough and effective update
on models relevant to esophageal metaplasia, dysplasia, and carcinogenesis, focusing on …

Esophageal cancer is of high importance to occurrence, development, and treatment
resistance. As evidenced by recent studies, pathways (eg, Wnt/β‐catenin, AMPK, and Hippo) …