Epilepsy is a common neurological disorder, affecting patients of all ages, reducing the
quality of life, and associated with several comorbidities. Sleep impairment is a frequent …

Abstract Purpose of Review To review the mutual interactions between sleep and epilepsy,
including mechanisms of epileptogenesis, the relationship between sleep apnea and …

Rotigotine (RTG) is a non-ergoline dopamine agonist and an approved drug for treating
Parkinson's disease. However, its clinical use is limited due to various problems, viz. poor …

Epilepsies are common chronic neurological diseases characterized by recurrent
unprovoked seizures of central origin. The mainstay of treatment involves symptomatic …

The correlation between sleep and epilepsy has been argued over the past decades among
scientists. Although the similarities and contrasts between sleep and epilepsy had been …

Rotigotine (RTG) is an anti-Parkinson's drug approved by the USFDA to treat motor and non-
motor symptoms of both early and advanced stages of the disease. However, issues like …

Lateral hypothalamic (LH) hypocretin/orexin neurons (HONs) control brain-wide electrical
excitation. Abnormally high excitation produces epileptic seizures, which affect millions of …

The orexin system consists of the peptide transmitters orexin-A and-B and the G protein-
coupled orexin receptors OX 1 and OX 2. Orexin receptors are capable of coupling to all four …

Objective Immediately preceding sudden unexpected death in epilepsy (SUDEP), patients
experienced a final generalized tonic‐clonic seizure (GTCS), rapid ventilation, apnea …

Two-way active avoidance (TWAA) acquisition constitutes a particular case of approach–
avoidance conflict for laboratory rodents. The present article reviews behavioural …