The tumor stroma is no longer seen solely as physical support for mutated epithelial cells but
as an important modulator and even a driver of tumorigenicity. Within the tumor stromal …

The aim of the present study was to perform a systematic review of published studies to
provide a robust estimation of the use of procalcitonin (ProCT) as a diagnostic marker of …

Carcinoma-associated fibroblasts (CAF) mediate the onset of a proinvasive tumour
microenvironment. The proinflammatory cytokine LIF reprograms fibroblasts into a …

The growth and progression of solid tumors involves dynamic cross-talk between cancer
epithelium and the surrounding microenvironment. To date, molecular profiling has largely …

Heterogeneous prostatic carcinoma-associated fibroblasts (CAF) contribute to tumor
progression and resistance to androgen signaling deprivation therapy (ADT). CAF subjected …

Simple Summary The tumour microenvironment contains a unique population of cells, of
complex origin and diverse functionality, known as Cancer associated fibroblasts (CAFs). In …

Prostate cancer is an androgen-dependent disease subject to interactions between the
tumor epithelium and its microenvironment. Here, we found that epigenetic changes in …

Abstract Cancer-associated fibroblasts (CAFs), a significant component of the tumor
microenvironment (TME), contribute to cancer progression through the secretion of …

Metastasis causes more than 90% of cancer-related deaths and most prostate cancer (PCa)
patients also die from metastasis. The 'metastatic cascade'is a complex biological process …

Colorectal carcinogenesis (CRC) is caused by the gradual long-term accumulation of both
genetic and epigenetic changes. Recently, epigenetic alterations have been included in the …