Cognitive impairment is an increasingly recognized major cause of chronic disability and is
commonly found in patients with chronic kidney disease (CKD). Knowledge of the …

Objective Frailty is associated with increased vulnerability to poor health. There is growing
interest in understanding the association between frailty and chronic kidney disease (CKD) …

Objective: To test whether frailty, a novel measure of physiologic reserve, is associated with
longer kidney transplant (KT) length of stay (LOS), and modifies the association between …

Background Among community-dwelling older adults, frailty is associated with heightened
markers of inflammation and subsequent mortality. Although frailty is common among end …

Background Frailty increases early hospital readmission and mortality risk among kidney
transplantation (KT) recipients. Although frailty represents a high-risk state for this …

Results The mean age was 54 years (SD 13; range, 18–89), 40% were women, 34% were
black, and 21% were frail. Frail participants were almost half as likely to be listed for kidney …

Background Health-related quality of life (HRQOL) reflects a patient's disease burden,
treatment effectiveness, and health status and is summarized by physical, mental, and …

Background Frailty is characterized by the loss of biological reserves and vulnerability to
adverse outcomes. In individuals with chronic kidney disease (CKD), numerous …

Background Frailty is a multidimensional syndrome characterized by loss of physiologic and
cognitive reserve that heightens vulnerability. Frailty has been well described among elderly …

Background Restoration of kidney function after kidney transplant generally improves
cognitive function. It is unclear whether frail recipients, with higher susceptibility to surgical …