Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …

Zebrafish are widely considered an excellent vertebrate model for studying the
pathogenesis of human diseases because of their transparency of embryonic development …

The ubiquitous use of ethinylestradiol (EE2), an active constituent of birth control
preparations, results in continuous release of this synthetic estrogen to surface waters. Many …

The rapid development of scRNA-seq technology in recent years has enabled us to capture
high-throughput gene expression profiles at single-cell resolution, reveal the heterogeneity …

Background: Iron trafficking and accumulation is associated with Alzheimer's disease (AD)
pathogenesis. However, the role of iron dyshomeostasis in early disease stages is …

The prevalence of neurodegenerative diseases is increasing globally, with an imperative
need to identify and expand the availability of pharmaceutical treatment strategies …

Aging entails gradual functional decline influenced by interconnected factors. Multiple
hallmarks proposed as common and conserved underlying denominators of aging on the …

Danio rerio is a model organism used to investigate vertebrate development. Manipulation
of the zebrafish genome and resultant gene products by mutation or targeted knockdown …

Brain-specific SIRT6-KO mice present increased DNA damage, learning impairments, and
neurodegenerative phenotypes, placing SIRT6 as a key protein in preventing …

Recent developments in nanotechnology has increased the market value of nanoproducts in
various industries. This has increased concerns associated with potential toxicity of …