A review of exosomal isolation methods: is size exclusion chromatography the best option?

K Sidhom, PO Obi, A Saleem - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and
eukaryotic cells and play a vital role in intercellular communication. EVs are classified into …

[HTML][HTML] Progress, opportunity, and perspective on exosome isolation-efforts for efficient exosome-based theranostics

D Yang, W Zhang, H Zhang, F Zhang, L Chen, L Ma… - Theranostics, 2020 - ncbi.nlm.nih.gov
Exosomes are small extracellular vesicles with diameters of 30-150 nm. In both
physiological and pathological conditions, nearly all types of cells can release exosomes …

[HTML][HTML] Regulation of exosome production and cargo sorting

H Wei, Q Chen, L Lin, C Sha, T Li, Y Liu… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Cellular communication can be mediated by the exchange of biological information, mainly
in the form of proteins and RNAs. This can occur when extracellular vesicles, such as …

Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes

S Gurunathan, MH Kang, M Jeyaraj, M Qasim, JH Kim - Cells, 2019 - mdpi.com
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …

Extracellular vesicles: A bright star of nanomedicine

P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery

VP Chavda, A Pandya, L Kumar, N Raval, LK Vora… - Nano Today, 2023 - Elsevier
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

Technologies and standardization in research on extracellular vesicles

S Gandham, X Su, J Wood, AL Nocera, SC Alli… - Trends in …, 2020 - cell.com
Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …

Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation

H Zhang, D Freitas, HS Kim, K Fabijanic, Z Li… - Nature cell …, 2018 - nature.com
The heterogeneity of exosomal populations has hindered our understanding of their
biogenesis, molecular composition, biodistribution and functions. By employing asymmetric …

New technologies for analysis of extracellular vesicles

H Shao, H Im, CM Castro, X Breakefield… - Chemical …, 2018 - ACS Publications
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Isolation of extracellular vesicles: general methodologies and latest trends

MY Konoshenko, EA Lekchnov… - BioMed research …, 2018 - Wiley Online Library
Background. Extracellular vesicles (EVs) play an essential role in the communication
between cells and transport of diagnostically significant molecules. A wide diversity of …