Repair and regeneration of human tissues and organs using biomaterials, cells, and/or
growth factors is a great challenge for tissue engineers and surgeons. The convergence of …

The number of patients with bone defects caused by various bone diseases is increasing
yearly in the aging population, and people are paying increasing attention to bone tissue …

The differentiation of osteoblasts from their precursors, mesenchymal stem cells, is an
important component of bone homeostasis as well as fracture healing. The A2B adenosine …

The purpose of this study was to determine the critical time periods of melatonin treatment
required to induce human mesenchymal stem cells (hAMSCs) into osteoblasts and to …

AIM: Glucagon-like peptide-1 (GLP-1) receptor participates in the control of bone resorption
in GLP-1 knockout mice. Also, GLP-1 induces an insulin-and parathyroid hormone …

Skeletal (marrow stromal) stem cells (BMSCs) are a group of multipotent cells that reside in
the bone marrow stroma and can differentiate into osteoblasts, chondrocytes and …

Patients with diabetes tend to have an increased incidence of osteoporosis that may be
related to hyperglycemia. In this study, we investigated the effects of high glucose on …

Previous studies have proven that glucagon-like peptide-1 (GLP-1) and its receptor agonist
exert favorable anabolic effects on skeletal metabolism. However, whether GLP-1 could …

Molecules such as growth factors, peptides and small molecules can guide cellular behavior
and are thus important for tissue engineering. They are rapidly emerging as promising …

Antipsychotics are commonly used in treating psychiatric disorders. These medications
primarily target dopamine the serotonin receptors, they have some affinity to adrenergic …