Recent advances and trends in aptasensors for sensitive detection of foodborne pathogens in various foods

Y Song, W Li, H Xu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Foodborne pathogens are found mainly in various foods and have become a great threat to
human. Although traditional methods can achieve effective analytical, they are time …

The JAK-STAT pathway at twenty

GR Stark, JE Darnell - Immunity, 2012 - cell.com
We look back on the discoveries that the tyrosine kinases TYK2 and JAK1 and the
transcription factors STAT1, STAT2, and IRF9 are required for the cellular response to type I …

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

JE Darnell Jr, M Kerr, GR Stark - Science, 1994 - science.org
Through the study of transcriptional activation in response to interferon α (IFN-α) and
interferon γ (IFN-γ), a previously unrecognized direct signal transduction pathway to the …

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

R Sen, D Baltimore - cell, 1986 - cell.com
To characterize proteins that bind to the immunoglobulin (lg) heavy chain and the K light
chain enhancers, an electrophoretic mobility shift assay with end-labeled DNA fragments …

Electrophoretic mobility shift assay (EMSA) for detecting protein–nucleic acid interactions

LM Hellman, MG Fried - Nature protocols, 2007 - nature.com
The gel electrophoresis mobility shift assay (EMSA) is used to detect protein complexes with
nucleic acids. It is the core technology underlying a wide range of qualitative and …

Maximal activation of transcription by Statl and Stat3 requires both tyrosine and serine phosphorylation

Z Wen, Z Zhong, JE Darnell Jr - Cell, 1995 - cell.com
Statl and Stat3 are latent transcriptional factors activated initially through phosphorylation on
single tyrosine residues induced by cytokine and growth factor occupation of cell surface …

Metabolite sensing and signaling in cell metabolism

YP Wang, QY Lei - Signal transduction and targeted therapy, 2018 - nature.com
Metabolite sensing is one of the most fundamental biological processes. During evolution,
multilayered mechanisms developed to sense fluctuations in a wide spectrum of …

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

Z Cao, RM Umek, SL McKnight - Genes & development, 1991 - genesdev.cshlp.org
In an effort to identify protein factors that play a regulatory role in the differentiation of
adipocytes, we have isolated two genes that encode polypeptides related to …

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

PJ Mitchell, R Tjian - Science, 1989 - science.org
The cloning of genes encoding mammalian DNA binding transcription factors for RNA
polymerase II has provided the opportunity to analyze the structure and function of these …

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

G Nabel, D Baltimore - Nature, 1987 - nature.com
Human immunodeficiency virus (HIV) production from latently infected T lymphocytes can be
induced with compounds that activate the cells to secrete lymphokines1, 2. The elements in …