Lab-on-a-chip: a component view

YC Lim, AZ Kouzani, W Duan - Microsystem Technologies, 2010 - Springer
Miniaturization is being increasingly applied to biological and chemical analysis processes.
Lab-on-a-chip systems are direct creation of the advancement in the miniaturization of these …

Optofluidic integration for microanalysis

HC Hunt, JS Wilkinson - Microfluidics and Nanofluidics, 2008 - Springer
This review describes recent research in the application of optical techniques to microfluidic
systems for chemical and biochemical analysis. The “lab-on-a-chip” presents great benefits …

Micro total analysis systems: latest achievements

J West, M Becker, S Tombrink, A Manz - Analytical chemistry, 2008 - ACS Publications
The field of micro total analysis systems (μTAS), or “lab on a chip”, has continued to gain
maturity. The importance of μTAS is reflected in both the growing number and the improved …

[HTML][HTML] High-throughput screening for high-efficiency small-molecule biosynthesis

M Rienzo, SJ Jackson, LK Chao, T Leaf, TJ Schmidt… - Metabolic …, 2021 - Elsevier
Abstract Systems metabolic engineering faces the formidable task of rewiring microbial
metabolism to cost-effectively generate high-value molecules from a variety of inexpensive …

Broad-band spectrum, high-sensitivity absorbance spectroscopy in picoliter volumes

J Probst, P Howes, P Arosio, S Stavrakis… - Analytical …, 2021 - ACS Publications
Picoliter-volume droplets within segmented flows can be probed in a rapid and efficient
manner using optical detection methods. To date, however, most detection schemes for …

Label-free physical techniques and methodologies for proteins detection in microfluidic biosensor structures

G Konoplev, D Agafonova, L Bakhchova, N Mukhin… - Biomedicines, 2022 - mdpi.com
Proteins in biological fluids (blood, urine, cerebrospinal fluid) are important biomarkers of
various pathological conditions. Protein biomarkers detection and quantification have been …

Modular integration of electronics and microfluidic systems using flexible printed circuit boards

A Wu, L Wang, E Jensen, R Mathies, B Boser - Lab on a Chip, 2010 - pubs.rsc.org
Microfluidic systems offer an attractive alternative to conventional wet chemical methods with
benefits including reduced sample and reagent volumes, shorter reaction times, high …

Real-time intrinsic fluorescence visualization and sizing of proteins and protein complexes in microfluidic devices

PK Challa, Q Peter, MA Wright, Y Zhang… - Analytical …, 2018 - ACS Publications
Optical detection has become a convenient and scalable approach to read out information
from microfluidic systems. For the study of many key biomolecules, however, including …

Fully integrated microfluidic separations systems for biochemical analysis

GT Roman, RT Kennedy - Journal of Chromatography A, 2007 - Elsevier
Over the past decade a tremendous amount of research has been performed using
microfluidic analytical devices to detect over 200 different chemical species. Most of this …

[PDF][PDF] Microfabrication of biomedical lab-on-chip devices. A review

AT Giannitsis - Estonian Journal of Engineering, 2011 - kirj.ee
Lab-on-chip systems are a class of miniaturized analytical devices that integrate fluidics,
electronics and various sensorics. They are capable of analysing biochemical liquid …