Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting

AS Wattiez, LP Sowers, AF Russo - Expert opinion on therapeutic …, 2020 - Taylor & Francis
Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …

[HTML][HTML] The role of endothelial dysfunction in the pathophysiology and cerebrovascular effects of migraine: a narrative review

M Paolucci, C Altamura, F Vernieri - Journal of Clinical Neurology …, 2021 - ncbi.nlm.nih.gov
Background and Purpose Migraine is a complex neurovascular disorder whose triggers are
not entirely understood. Endothelial dysfunction might play a role in migraine, and there …

Oxidative stress and decreased thiol level in patients with migraine: cross-sectional study

Y Eren, E Dirik, S Neşelioğlu, Ö Erel - Acta Neurologica Belgica, 2015 - Springer
Although migraine is a neurological disorder known since long, its physiopathology remains
unclear. Recent studies suggest that migraine is associated with oxidative stress; however …

The biological axis of protein arginine methylation and asymmetric dimethylarginine

MD Fulton, T Brown, YG Zheng - International journal of molecular …, 2019 - mdpi.com
Protein post-translational modifications (PTMs) in eukaryotic cells play important roles in the
regulation of functionalities of the proteome and in the tempo-spatial control of cellular …

Endothelial progenitor cells: a new key for endothelial dysfunction in migraine

X Rodríguez-Osorio, T Sobrino, D Brea, F Martinez… - Neurology, 2012 - AAN Enterprises
Objective: We aimed to study endothelial function with biochemical and ultrasonographic
markers and its relation with endothelial progenitor cells (EPCs) in patients with migraine …

Biomarkers of migraine: an integrated evaluation of preclinical and clinical findings

C Demartini, M Francavilla, AM Zanaboni… - International journal of …, 2023 - mdpi.com
In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …

[HTML][HTML] White matter lesions in migraine

K Eikermann-Haerter, SY Huang - The American journal of pathology, 2021 - Elsevier
Migraine, the third most common disease worldwide, is a well-known independent risk factor
for subclinical focal deep white matter lesions (WMLs), even in young and otherwise healthy …

CGRP and PTX3 as predictors of efficacy of Onabotulinumtoxin type a in chronic migraine: an observational study

C Domínguez, A Vieites‐Prado… - … : The Journal of …, 2018 - Wiley Online Library
Objective The aim of this study is to find a relation between several biomarkers in peripheral
blood and outcome after treatment with onabotulinumtoxin A (OnabotA). Background …

Vascular biomarkers in migraine

GE Tietjen, J Khubchandani - Cephalalgia, 2015 - journals.sagepub.com
Aim Migraine has been associated with stroke as well as with several non-atherosclerotic
vascular conditions leading to discussions about the potential role of endothelium in the …

Dysregulation of amino acid, lipid, and acylpyruvate metabolism in idiopathic intracranial hypertension: A non-targeted case control and longitudinal metabolomic …

Z Alimajstorovic, SP Mollan, O Grech… - Journal of Proteome …, 2022 - ACS Publications
Background: Idiopathic intracranial hypertension (IIH) is characterized by increased
intracranial pressure occurring predominantly in women with obesity. The pathogenesis is …