In recent years, there has been a dramatic rise in interest in retrosynthesis prediction with
artificial intelligence (AI) techniques. Unlike conventional retrosynthesis prediction …

Pyrroloindolines are important and privileged polycyclic indoline motifs that are widely
present in natural products and bio-significant molecules. From an organic chemistry …

Alcohols are abundant with versatile structural variety and have ample use as pivotal
functional groups in numerous organic processes. Because of their frequent occurrence in …

Natural products containing eight-membered carbocycles constitute a class of structurally
intriguing and biologically important molecules such as the famous diterpenes taxol and …

The total synthesis of natural products is constantly facing many challenges derived from the
complexed chemical structures, the lengthy synthetic routes, the time-consuming workup …

With a number of antibody–drug conjugates (ADCs) approved for clinical use as targeted
cancer therapies and numerous candidates in clinical trials, the field of ADCs is emerging as …

Covering: 1970 to 2020 By definition total synthesis is the art and science of making the
molecules of living Nature in the laboratory, and by extension, their analogues. Although …

Pnictogen‐bonding catalysis and supramolecular σ‐hole catalysis in general is currently
being introduced as the non‐covalent counterpart of covalent Lewis acid catalysis. With …

Efficient and modular synthesis of structurally diverse 1, 4-diketones from readily available
building blocks represents an essential but challenging task in organic chemistry. Herein …

Perovskite solar cells are a leading contender in the race to become the next commercially
viable photovoltaic technology. Over the past decade, significant advancements have been …