Safe surgery for glioblastoma: Recent advances and modern challenges

JKW Gerritsen, MLD Broekman… - Neuro-oncology …, 2022 - academic.oup.com
One of the major challenges during glioblastoma surgery is balancing between maximizing
extent of resection and preventing neurological deficits. Several surgical techniques and …

Current applications of diffusion tensor imaging and tractography in intracranial tumor resection

JD Costabile, E Alaswad, S D'Souza… - Frontiers in …, 2019 - frontiersin.org
In the treatment of brain tumors, surgical intervention remains a common and effective
therapeutic option. Recent advances in neuroimaging have provided neurosurgeons with …

Is Ki-67 index overexpression in IDH wild type glioblastoma a predictor of shorter Progression Free survival? A clinical and Molecular analytic investigation

D Armocida, A Frati, M Salvati, A Santoro… - Clinical Neurology and …, 2020 - Elsevier
Background Ki-67 proliferation index is widely used for differentiating between high and low-
grade gliomas, but differentiating between the same grade IV appears to be more …

Can preoperative mapping with functional MRI reduce morbidity in brain tumor resection? A systematic review and meta-analysis of 68 observational studies

LP Luna, FG Sherbaf, HI Sair, D Mukherjee, IB Oliveira… - Radiology, 2021 - pubs.rsna.org
Background Preoperative functional MRI (fMRI) is one of several techniques developed to
localize critical brain structures and brain tumors. However, the usefulness of fMRI for …

EGFR amplification is a real independent prognostic impact factor between young adults and adults over 45yo with wild-type glioblastoma?

D Armocida, A Pesce, A Frati, A Santoro… - Journal of Neuro …, 2020 - Springer
Background In 2019 a group of University of Pennsylvania (Hoffman et al., J Neurooncol
145: 321–328, 2019) aimed to explore the prognostic impact of expression of epidermal …

Diffusion tractography for awake craniotomy: accuracy and factors affecting specificity

NL Voets, P Pretorius, MD Birch… - Journal of Neuro …, 2021 - Springer
Introduction Despite evidence of correspondence with intraoperative stimulation, there
remains limited data on MRI diffusion tractography (DT)'s sensitivity to predict morbidity after …

IDH wild-type glioblastoma presenting with seizure: clinical specificity, and oncologic and surgical outcomes

A Pesce, D Armocida, F Paglia… - … Surgery Part A …, 2022 - thieme-connect.com
Background Glioblastoma (GBM) is the most common and aggressive primary brain
neoplasia in adults. Seizure is a common manifestation in GBM. Up to 25 to 60% of patients …

Histological, molecular, clinical and outcomes characteristics of Multiple Lesion Glioblastoma. A retrospective monocentric study and review of literature

D Armocida, A Pesce, F Di Giammarco, A Frati… - Neurocirugia, 2021 - Elsevier
Background Multiple lesion glioblastoma (M-GBM) represent a group of GBM patients in
which there exist multiple foci of tumor enhancement. The prognosis is poorer than that of …

[HTML][HTML] Periventricular zone involvement as a predictor of survival in glioblastoma patients: A single centre cohort-comparison investigation concerning a distinct …

D Armocida, A Pesce, M Palmieri, G D'Andrea… - Interdisciplinary …, 2021 - Elsevier
Background Glioblastoma (GBM) contacting the Subventricular Zone (SVZ) may display a
more aggressive pattern of invasiveness with higher potential to recruit migratory progenitor …

Role of endoscopic surgical biopsy in diagnoses of intraventricular/periventricular tumors: Review of literature including a monocentric case series

L D'Angelo, D Armocida, L Sampirisi, F Paglia… - Acta Neurologica …, 2020 - Springer
The intra-and periventricular location tumor (IPVT) of a brain remains a hard challenge for
the neurosurgeon because of the deep location and eloquent anatomic associations. Due to …