Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

The effect of bacterial chemotaxis on host infection and pathogenicity

MA Matilla, T Krell - FEMS Microbiology Reviews, 2018 - academic.oup.com
Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Sensory repertoire of bacterial chemoreceptors

Á Ortega, IB Zhulin, T Krell - Microbiology and Molecular Biology …, 2017 - Am Soc Microbiol
Chemoreceptors in bacteria detect a variety of signals and feed this information into
chemosensory pathways that represent a major mode of signal transduction. The five …

Role of Flagella in the Pathogenesis of Helicobacter pylori

H Gu - Current microbiology, 2017 - Springer
This review aimed to investigate the role of Helicobacter pylori flagella on the pathogenicity
of this bacterium in humans. Helicobacter pylori is a flagellated pathogen that colonizes the …

Survival of Helicobacter pylori in gastric acidic territory

S Ansari, Y Yamaoka - Helicobacter, 2017 - Wiley Online Library
Background Helicobacter pylori is well adapted to colonize the epithelial surface of the
human gastric mucosa and can cause persistent infections. In order to infect the gastric …

State of the art of bacterial chemotaxis

R Karmakar - Journal of Basic Microbiology, 2021 - Wiley Online Library
Bacterial chemotaxis is a biased movement of bacteria toward the beneficial chemical
gradient or away from a toxic chemical gradient. This movement is achieved by sensing a …

Chemodetection and destruction of host urea allows Helicobacter pylori to locate the epithelium

JY Huang, EG Sweeney, M Sigal, HC Zhang… - Cell host & …, 2015 - cell.com
The gastric pathogen Helicobacter pylori interacts intimately with the gastric mucosa to avoid
the microbicidal acid in the stomach lumen. The cues H. pylori senses to locate and colonize …

Adhesion and Invasion of Gastric Mucosa Epithelial Cells by Helicobacter pylori

Y Huang, Q Wang, D Cheng, W Xu… - Frontiers in cellular and …, 2016 - frontiersin.org
Helicobacter pylori is the main pathogenic bacterium involved in chronic gastritis and peptic
ulcer and a class 1 carcinogen in gastric cancer. Current research focuses on the …

Survival in hostile territory: the microbiota of the stomach

I Yang, S Nell, S Suerbaum - FEMS microbiology reviews, 2013 - academic.oup.com
The human stomach is a formidable barrier to orally ingested microorganisms and was long
thought to be sterile. The discovery of Helicobacter pylori, a carcinogenic bacterial pathogen …

Colonization, localization, and inflammation: the roles of H. pylori chemotaxis in vivo

KS Johnson, KM Ottemann - Current opinion in microbiology, 2018 - Elsevier
Highlights•The Helicobacter pylori chemotaxis system includes classical and auxiliary
chemotaxis proteins.•H. pylori senses several host and bacterial ligands through four …