Metabolic engineering advances and prospects for amino acid production
VF Wendisch - Metabolic engineering, 2020 - Elsevier
Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …
Advances in metabolic engineering of Corynebacterium glutamicum to produce high-value active ingredients for food, feed, human health, and well-being
S Wolf, J Becker, Y Tsuge, H Kawaguchi… - Essays in …, 2021 - portlandpress.com
The soil microbe Corynebacterium glutamicum is a leading workhorse in industrial
biotechnology and has become famous for its power to synthetise amino acids and a range …
biotechnology and has become famous for its power to synthetise amino acids and a range …
[HTML][HTML] Microbial production of extremolytes—high-value active ingredients for nutrition, health care, and well-being
J Becker, C Wittmann - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Extremolytes protect extremophilic microbes from environmental stress.•They
enable multiple applications in cosmetics, food, and health industry.•Ectoine is the industrial …
enable multiple applications in cosmetics, food, and health industry.•Ectoine is the industrial …
Lysine catabolism through the saccharopine pathway: enzymes and intermediates involved in plant responses to abiotic and biotic stress
P Arruda, P Barreto - Frontiers in plant science, 2020 - frontiersin.org
The saccharopine pathway (SACPATH) involves the conversion of lysine into α-
aminoadipate by three enzymatic reactions catalyzed by the bifunctional enzyme lysine …
aminoadipate by three enzymatic reactions catalyzed by the bifunctional enzyme lysine …
[HTML][HTML] Systems metabolic engineering upgrades Corynebacterium glutamicum for selective high-level production of the chiral drug precursor and cell-protective …
S Pauli, M Kohlstedt, J Lamber, F Weiland, J Becker… - Metabolic …, 2023 - Elsevier
The nonproteinogenic cyclic metabolite l-pipecolic acid is a chiral precursor for the synthesis
of various commercial drugs and functions as a cell-protective extremolyte and mediator of …
of various commercial drugs and functions as a cell-protective extremolyte and mediator of …
Salicylic Acid and N-Hydroxypipecolic Acid at the Fulcrum of the Plant Immunity-Growth Equilibrium
A Shields, V Shivnauth, CDM Castroverde - Frontiers in Plant Science, 2022 - frontiersin.org
Salicylic acid (SA) and N-hydroxypipecolic acid (NHP) are two central plant immune signals
involved in both resistance at local sites of pathogen infection (basal resistance) and at …
involved in both resistance at local sites of pathogen infection (basal resistance) and at …
Fermentative indole production via bacterial tryptophan synthase alpha subunit and plant indole-3-glycerol phosphate lyase enzymes
L Ferrer, M Mindt, M Suarez-Diez, T Jilg… - Journal of Agricultural …, 2022 - ACS Publications
Indole is produced in nature by diverse organisms and exhibits a characteristic odor
described as animal, fecal, and floral. In addition, it contributes to the flavor in foods, and it is …
described as animal, fecal, and floral. In addition, it contributes to the flavor in foods, and it is …
[HTML][HTML] Priming for drought resistance: UV-C flashes triggered pipecolate accumulation and dehydration avoidance in Capsicum chinense Jacq. but induced no …
C Pons, L Mas-Normand, O Chevallier, J Aarrouf… - Environmental and …, 2024 - Elsevier
Ultraviolet (UV) radiation has been increasingly studied as an elicitor of plant defense
against biotic and abiotic stress. The biological responses to these stimuli can be either …
against biotic and abiotic stress. The biological responses to these stimuli can be either …
De novo tryptophanase-based indole production by metabolically engineered Corynebacterium glutamicum
Indole has an increasing interest in the flavor and fragrance industry. It is used in dairy
products, tea drinks, and fine fragrances due to its distinct floral odor typical of jasmine …
products, tea drinks, and fine fragrances due to its distinct floral odor typical of jasmine …
Metabolic Engineering for Valorization of Agri- and Aqua-Culture Sidestreams for Production of Nitrogenous Compounds by Corynebacterium glutamicum
VF Wendisch, KM Nampoothiri, JH Lee - Frontiers in Microbiology, 2022 - frontiersin.org
Corynebacterium glutamicum is used for the million-ton-scale production of amino acids.
Valorization of sidestreams from agri-and aqua-culture has focused on the production of …
Valorization of sidestreams from agri-and aqua-culture has focused on the production of …