The prevalence of cardiomyopathy is higher in diabetic patients than those without diabetes.
Diabetic cardiomyopathy (DCM) is defined as a clinical condition of abnormal myocardial …

As a serious cardiovascular complication, diabetic cardiomyopathy (DCM) refers to diabetes‐
related changes in myocardial structure and function, which is obviously different from those …

Rationale: The rennin-angiotensin-aldosterone system (RAAS) plays a critical role in the
pathogenesis of diabetic cardiomyopathy, but the role of a member of RAAS, angiotensin IV …

Diabetes causes lipid peroxide to accumulate within cardiomyocytes. Furthermore, lipid
peroxide buildup is a risk factor for ferroptosis. This study is aimed at examining whether …

Background: Pyroptosis is an inflammatory programmed cell death accompanied by
activation of inflammasomes and maturation of pro-inflammatory cytokines interleukin-1β (IL …

Neurons critically depend on mitochondria for ATP production and Ca2+ buffering. They are
highly compartmentalized cells and therefore a finely tuned mitochondrial network …

Mitochondria play essential roles in cellular energetics, biosynthesis, and signaling
transduction. Dysfunctional mitochondria have been implicated in different diseases such as …

Diabetic cardiomyopathy (DCM) is a prevalent cardiovascular complication of diabetes
mellitus, characterized by high morbidity and mortality rates worldwide. However, treatment …

Summary Type 2 diabetes (T2D) increases the risk for diabetic cardiomyopathy and is
characterized by diastolic dysfunction. Myocardial forkhead box O1 (FoxO1) activity is …

Glycometabolism is well known for its roles as the main source of energy, which mainly
includes three metabolic pathways: oxidative phosphorylation, glycolysis and pentose …