Sequencing-based methods and resources to study antimicrobial resistance
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
Using genomics to track global antimicrobial resistance
RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
An omics-based framework for assessing the health risk of antimicrobial resistance genes
Antibiotic resistance genes (ARGs) are widespread among bacteria. However, not all ARGs
pose serious threats to public health, highlighting the importance of identifying those that are …
pose serious threats to public health, highlighting the importance of identifying those that are …
Global biogeography and projection of soil antibiotic resistance genes
Although edaphic antibiotic resistance genes (ARGs) pose serious threats to human well-
being, their spatially explicit patterns and responses to environmental constraints at the …
being, their spatially explicit patterns and responses to environmental constraints at the …
Probiotics impact the antibiotic resistance gene reservoir along the human GI tract in a person-specific and antibiotic-dependent manner
Antimicrobial resistance poses a substantial threat to human health. The gut microbiome is
considered a reservoir for potential spread of resistance genes from commensals to …
considered a reservoir for potential spread of resistance genes from commensals to …
Conjugative plasmids interact with insertion sequences to shape the horizontal transfer of antimicrobial resistance genes
It is well established that plasmids play an important role in the dissemination of
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
antimicrobial resistance (AMR) genes; however, little is known about the role of the …
Short-vs standard-course outpatient antibiotic therapy for community-acquired pneumonia in children: the SCOUT-CAP randomized clinical trial
Importance Childhood community-acquired pneumonia (CAP) is usually treated with 10
days of antibiotics. Shorter courses may be effective with fewer adverse effects and …
days of antibiotics. Shorter courses may be effective with fewer adverse effects and …
mobileOG-db: a manually curated database of protein families mediating the life cycle of bacterial mobile genetic elements
Bacterial mobile genetic elements (MGEs) encode functional modules that perform both core
and accessory functions for the element, the latter of which are often only transiently …
and accessory functions for the element, the latter of which are often only transiently …
Strain-level characterization of broad host range mobile genetic elements transferring antibiotic resistance from the human microbiome
Mobile genetic elements (MGEs) carrying antibiotic resistance genes (ARGs) disseminate
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
ARGs when they mobilise into new bacterial hosts. The nature of such horizontal gene …
Deciphering the mobility and bacterial hosts of antibiotic resistance genes under antibiotic selection pressure by metagenomic assembly and binning approaches
The presence of antibiotics can exert significant selection pressure on the emergence and
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) …
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) …