Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Helicobacter pylori are spiral-shaped gram-negative bacteria with polar flagella that live
near the surface of the human gastric mucosa. They have evolved intricate mechanisms to …

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a
systematic analysis for the Glo Page 1 Global Health Metrics 1204 www.thelancet.com Vol 396 …

The discovery of Helicobacter pylori overturned the conventional dogma that the stomach
was a sterile organ and that pH values< 4 were capable of sterilizing the stomach. H. pylori …

Gastric cancer remains a global killer with a shifting burden from the developed to the
developing world. The cancer develops along a multistage process that is defined by distinct …

Although scientific knowledge in viral oncology has exploded in the 20th century, the role of
bacteria as mediators of oncogenesis has been less well elucidated. Understanding …

Background Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have
been reported to impact gastric inflammation and carcinogenesis. However, the precise …

To evaluate the association between gastric cancer susceptibility and inflammation-related
gene polymorphisms, the authors conducted a series of meta-analyses using a predefined …

Background: Polymorphisms of interleukin-1B (IL1B) and its receptor antagonist (IL1RN)
genes have been inconsistently associated with gastric cancer risk. We examined these …

Chronic inflammation may increase the risk to develop cancer, for instance esophagitis or
gastritis may lead to development of esophageal or gastric cancer, respectively. The key …