[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …

Effects of waterborne antidepressants on non-target animals living in the aquatic environment: a review

P Sehonova, Z Svobodova, P Dolezelova… - Science of the Total …, 2018 - Elsevier
After application, antidepressants, like other pharmaceuticals, are excreted from human
body in their native form or as metabolites and enter the aquatic environment via different …

Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines …

DS Baldwin, IM Anderson, DJ Nutt… - Journal of …, 2014 - journals.sagepub.com
This revision of the 2005 British Association for Psychopharmacology guidelines for the
evidence-based pharmacological treatment of anxiety disorders provides an update on key …

Adverse effects of antidepressant medications and their management in children and adolescents

JR Strawn, JA Mills, EA Poweleit… - … : The Journal of …, 2023 - Wiley Online Library
Introduction Selective serotonin reuptake inhibitors (SSRIs) and, to a lesser extent, serotonin‐
norepinephrine reuptake inhibitors (SNRIs) are the cornerstone of pharmacotherapy for …

MAOA gene hypomethylation in panic disorder—reversibility of an epigenetic risk pattern by psychotherapy

C Ziegler, J Richter, M Mahr, A Gajewska… - Translational …, 2016 - nature.com
Epigenetic signatures such as methylation of the monoamine oxidase A (MAOA) gene have
been found to be altered in panic disorder (PD). Hypothesizing temporal plasticity of …

Understanding the effects of serotonin in the brain through its role in the gastrointestinal tract

JM Shine, C O'Callaghan, IC Walpola, G Wainstein… - Brain, 2022 - academic.oup.com
The neuromodulatory arousal system imbues the nervous system with the flexibility and
robustness required to facilitate adaptive behaviour. While there are well understood …

[HTML][HTML] Effect of zuranolone on concurrent anxiety and insomnia symptoms in women with postpartum depression

KM Deligiannidis, L Citrome, MY Huang… - The Journal of …, 2023 - psychiatrist.com
Objective: Concurrent anxiety and/or insomnia symptoms in women with postpartum
depression (PPD) are common and associated with more severe PPD. The effects of …

Sequential drug treatment algorithm for agitation and aggression in Alzheimer's and mixed dementia

SJC Davies, AM Burhan, D Kim… - Journal of …, 2018 - journals.sagepub.com
Introduction: Behavioural and psychological symptoms of dementia (BPSD) include agitation
and aggression in people with dementia. BPSD is common on inpatient psychogeriatric …

Activity of raphé serotonergic neurons controls emotional behaviors

A Teissier, A Chemiakine, B Inbar, S Bagchi, RS Ray… - Cell reports, 2015 - cell.com
Despite the well-established role of serotonin signaling in mood regulation, causal
relationships between serotonergic neuronal activity and behavior remain poorly …

Demystifying serotonin syndrome (or serotonin toxicity)

AL Foong, KA Grindrod, T Patel, J Kellar - Canadian Family Physician, 2018 - cfp.ca
Objective To review the symptoms of serotonin toxicity (commonly referred to as serotonin
syndrome) and the causative drugs and their mechanisms of action, and to equip primary …